Ertugliflozin impurity 8 CAS 1528636-47-6
| CAS No. | 1528636-47-6 |
| Molecular Formula | C22H25ClO8 |
| Molecular Weight | 452.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ertugliflozin impurity 8 (C22H25ClO8) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Ertugliflozin impurity 8 (CAS 1528636-47-6), a pharmacopoeial impurity reference standard (molecular formula C22H25ClO8, MW 452.88 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25ClO8 |
| Molecular Weight | 452.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
Related Ertugliflozin Standards
- Ertugliflozin impurity 22 (CAS 1298086-28-8)
- Ertugliflozin Impurity 50 (CAS 1298086-33-5)
- Ertugliflozin Impurity 51 (CAS 1298086-34-6)
- Ertugliflozin impurity 10 (CAS 1689522-89-1)
- Ertugliflozin impurity 3 (CAS 1298086-37-9)
- Ertugliflozin-d5 (CAS 1298086-22-2)
- Ertugliflozin impurity 24 (CAS CATO-C4X-301124)
- Ertugliflozin impurity 44 (CAS CATO-C4X-301144)
Recommended Standards
- 3-(3-Chloro-2-(cyclopropylamino)pyridin-4-yl)-2-(4-methoxybenzyl)-5-methyl-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4,6(5H)-dione (CAS 2316847-93-3)
- Methyl 3-(3-chlorobenzamido)-6-[(E)-2-[(3,5-dimethylphenyl)amino]ethenyl]-2-oxo-2H-pyran-5-carboxylate (CAS 341966-07-2)
- Allisartan Isoproxil Impurity 2 (CAS CATO-C4X-32172)
- Dapagliflozin Impurity 117 (CAS 2377899-45-9)
- Indobufen Impurity 69 (CAS CATO-C4X-179269)
- All-rac-alfa-Tocopheryl Acetate EP Impurity A（and Diastereoisomers） (CAS CATO-C4X-119518)
- Ceftibuten Impurity 2 (CAS CATO-C4X-18902)
- Vilanterol Impurity 78 (CAS CATO-C4X-193578)
- Methyl 3-(4-isopropyl-N-methylphenylsulfonamido)thiophene-2-carboxylate (CAS 1325304-90-2)
- Ethyl 3,5-dichloro-4-cyanopicolinate (CAS 1296172-36-5)
- Plerixafor Impurity 49 (CAS CATO-C4X-113349)
- 5,5-Dimethyl-2-phenyl-1,2,4-triazolidine-3-thione (CAS 39263-68-8)
- 2-(((2-Chlorothiazol-5-yl)methyl)amino)ethanol (CAS 1269145-75-6)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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