Risperidone EP Impurity C CAS 130049-85-3
| CAS No. | 130049-85-3 |
| Molecular Formula | C23H27FN4O3 |
| Molecular Weight | 426.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Risperidone EP Impurity C is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Risperidone EP Impurity C (CAS 130049-85-3), a pharmacopoeial impurity reference standard (molecular formula C23H27FN4O3, MW 426.48 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Risperidone EP Impurity C (C23H27FN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Risperidone EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H27FN4O3 |
| Molecular Weight | 426.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Risperidone Standards
- Risperidone Impurity 29 (CAS 832747-55-4)
- Risperidone Impurity 30 (CAS 1894509-66-0)
- Risperidone Impurity 39 (CAS CATO-C4X-111139)
- Risperidone Pyrimidinone-N-oxide (CAS 1301724-91-3)
- Risperidone EP Impurity C ((S)-Isomer) (CAS 147663-01-2)
- trans-Risperidone N-Oxide (CAS CATO-CP106668)
- Risperidone RC 23 (CAS 84163-48-4)
- 9-Methyl Risperidone (CAS 138271-01-9)
Recommended Standards
- Paliperidone (CAS 144598-75-4)
- Paliperidone Impurity 40 (CAS CATO-C4X-1724140)
- Paliperidone Impurity 35 (CAS 1346598-34-2)
- Roxadustat Impurity 153 (CAS CATO-C4X-2213153)
- Lenvatinib Impurity 97 (CAS 75955-30-5)
- Mivacurium chloride Impurity 54 (CAS CATO-C4X-137554)
- Cetilistat Impurity 2 (CAS CATO-C4X-11702)
- (S)-tert-Butyl 2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate, 97% (CAS 1007882-58-7)
- Methyl 4-Hydroxy-1-benzothiophene-6-carboxylate (CAS 314725-14-9)
- 2-Oxo-2-(4-(pentyloxy)phenyl)acetaldehyde (CAS 14333-55-2)
- Methyl 5-((8-methoxy-2-methyl-4-oxoquinolin-1(4H)-yl)methyl)furan-2-carboxylate (CAS 1216643-46-7)
- 1-(5-Nitropyridin-2-yl)-4-phenylpiperazine (CAS 400088-76-8)
- N-(2,2,2-Trichloro-1-(furan-2-yl)ethyl)benzenesulfonamide (CAS 114084-86-5)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com