Paliperidone Impurity 35 CAS 1346598-34-2
| CAS No. | 1346598-34-2 |
| Molecular Formula | C23H27FN4O3 |
| Molecular Weight | 426.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Paliperidone Impurity 35 (C23H27FN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Paliperidone Impurity 35 (CAS 1346598-34-2, C23H27FN4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Paliperidone Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H27FN4O3 |
| Molecular Weight | 426.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Paliperidone Standards
- Paliperidone (CAS 144598-75-4)
- Paliperidone Impurity 40 (CAS CATO-C4X-1724140)
- Paliperidone Impurity 97 (CAS CATO-C4X-172497)
- Paliperidone Impurity 115 (CAS CATO-C4X-1724115)
- Paliperidone Impurity 12 (CAS CATO-C4X-172412)
- Paliperidone Impurity 26 (CAS CATO-C4X-172426)
- Paliperidone Impurity 69 (CAS CATO-C4X-172469)
- Paliperidone Impurity 1 （Mixture of Tautomeric Isomers） (CAS 1189516-65-1)
Recommended Standards
- Risperidone EP Impurity C ((S)-Isomer) (CAS 147663-01-2)
- Risperidone EP Impurity C (CAS 130049-85-3)
- Roxadustat Impurity 153 (CAS CATO-C4X-2213153)
- trans-Risperidone N-Oxide (CAS CATO-CP106668)
- Nabumetone Impurity 25 (CAS CATO-C4X-284825)
- Eltrombopag Impurity 28 (CAS CATO-C4X-119828)
- Atropine Impurity 48 (CAS 3423-23-2)
- Biotin-PEG1-NH2 (CAS 811442-85-0)
- N-(2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1638329-59-5)
- 1,5-Cycloctadiene(acetylacetonate)rhodium(I) (CAS 12245-39-5)
- (3-(Furan-2-yl)isoxazol-5-yl)methanamine (CAS 27473-54-7)
- Ethyl (3-aminopropyl)(methyl)phosphinate (CAS 168977-85-3)
- Di-n-octyltin Oxide (CAS 870-08-6)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com