4-Methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide CAS 1301768-18-2
| CAS No. | 1301768-18-2 |
| Molecular Formula | C11H12F3NO2S |
| Molecular Weight | 279.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide.
CATO supplies 4-Methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide (CAS 1301768-18-2), a certified reference material (molecular formula C11H12F3NO2S, MW 279.28 g/mol) for analytical method development and quality control.
The molecular framework of 4-Methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide (C11H12F3NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F3NO2S |
| Molecular Weight | 279.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-Methyl-8-(trifluoromethyl)-2,3,4,5-tetrahydrobenzo[f][1,2]thiazepine 1,1-dioxide (CAS 1301768-19-3)
- 2-(3-(Trifluoromethyl)phenyl)benzo[d]thiazole (CAS 133389-19-2)
- 2-(4-(Trifluoromethyl)phenyl)benzo[d]thiazole (CAS 134384-31-9)
- 2-(2-(Trifluoromethyl)phenyl)benzo[d]thiazole (CAS 156215-39-3)
- 1-((3-(Trifluoromethyl)phenyl)sulfonyl)pyrrolidine (CAS 79392-45-3)
- 1-(4-((Trifluoromethyl)sulfonyl)phenyl)pyrrolidine (CAS 692279-06-4)
- 3-Phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine (CAS 882748-13-2)
- 2-(4-(Trifluoromethyl)phenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (CAS 1311186-65-8)
Recommended Standards
- 9-(3,5-Difluorophenyl)-9H-carbazole (CAS 1297473-29-0)
- (1R,5S)-rel-5-((tert-Butoxycarbonyl)amino)-3,3-difluorocyclohexanecarboxylic acid (CAS 1261225-61-9)
- 1-(tert-Butyl) 4-methyl 3,3-difluoropiperidine-1,4-dicarboxylate (CAS 1303973-86-5)
- 1-tert-Butyl 3-Ethyl 4,4-Difluoropyrrolidine-1,3-dicarboxylate (CAS 1260887-81-7)
- 3,5-Dichloro-N-methylbenzamide (CAS 33244-92-7)
- N1-(3-Fluorophenyl)-N2-(3-methoxybenzyl)oxalamide (CAS 708236-36-6)
- N,6-dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine (CAS 1355224-95-1)
- Methyl 4-[4-(2-methoxy-2-oxoethyl)phenyl]benzoate (CAS 1820647-75-3)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(3,4-dimethoxyphenyl)-3-hydroxy-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 488734-25-4)
- 2-((3,4-Dimethoxyphenyl)sulfonyl)acetonitrile (CAS 797036-29-4)
- Fmoc-L-leucinol (CAS 139551-83-0)
- 1,3-Dipalmitoyl-glycero-2-phosphoethanolamine (CAS 67303-93-9)
- 2,5-Difluoro-3-nitrobenzamide (CAS 1701869-33-1)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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