N1-(3-Fluorophenyl)-N2-(3-methoxybenzyl)oxalamide CAS 708236-36-6
| CAS No. | 708236-36-6 |
| Molecular Formula | C16H15FN2O3 |
| Molecular Weight | 302.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N1-(3-Fluorophenyl)-N2-(3-methoxybenzyl)oxalamide (CAS 708236-36-6), molecular formula C16H15FN2O3 and molecular weight 302.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N1-(3-Fluorophenyl)-N2-(3-methoxybenzyl)oxalamide (C16H15FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), N1-(3-Fluorophenyl)-N2-(3-methoxybenzyl)oxalamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15FN2O3 |
| Molecular Weight | 302.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-(2-Fluorophenyl)-5-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1443979-11-0)
- 1-(4-Fluorophenyl)-5-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1443979-15-4)
- 1-(2-Fluorophenyl)-4-(3-nitropyridin-2-yl)piperazine (CAS 400088-84-8)
- 1-(2-Fluorophenyl)-4-(5-nitro-2-pyridinyl)piperazine (CAS 400088-93-9)
- 1-(4-Fluorophenyl)-4-(3-nitropyridin-2-yl)piperazine (CAS 400088-90-6)
- 1-(4-Fluorophenyl)-4-(5-nitropyridin-2-yl)piperazine (CAS 400088-82-6)
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Recommended Standards
- N1-(2-Fluorobenzyl)-N2-(4-methoxyphenyl)oxalamide (CAS 847242-05-1)
- N1-(4-Fluorophenyl)-N2-(2-methoxybenzyl)oxalamide (CAS 428846-24-6)
- N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide (CAS 198572-71-3)
- Propan-2-yl 6-[(4-fluorophenyl)carbamoyl]pyridine-2-carboxylate (CAS 313516-11-9)
- 4,6-Dimethoxy-b-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) (CAS 159308-03-9)
- 2-Bromo-5-fluoro-4-nitroaniline (CAS 952664-69-6)
- benzyl (3S)-3-hydroxyazepane-1-carboxylate (CAS 1932807-60-7)
- 4-(Tetrahydrofuran-2-ylmethyl)-5-thien-2-yl-4H-1,2,4-triazole-3-thiol (CAS 438030-51-4)
- 4-Fluoro-DL-alpha-phenylglycine (CAS 7292-73-1)
- 1-(4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)-2,2-dimethylpropan-1-one (CAS 2390149-19-4)
- 6-(Tert-butyl)-2-((pyridin-4-ylmethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 354556-51-7)
- 2-(Difluoromethyl)benzo[d]oxazole-7-carboxaldehyde (CAS 1806340-41-9)
- 1-(4-Fluorophenyl)pyrrolidin-2-one (CAS 54660-08-1)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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