tert-Butyl 4-(aminomethyl)-3,3-difluoropiperidine-1-carboxylate CAS 1303973-22-9
| CAS No. | 1303973-22-9 |
| Molecular Formula | C11H20F2N2O2 |
| Molecular Weight | 250.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
tert-Butyl 4-(aminomethyl)-3,3-difluoropiperidine-1-carboxylate (CAS 1303973-22-9), molecular formula C11H20F2N2O2 and molecular weight 250.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-Butyl 4-(aminomethyl)-3,3-difluoropiperidine-1-carboxylate (C11H20F2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures tert-Butyl 4-(aminomethyl)-3,3-difluoropiperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H20F2N2O2 |
| Molecular Weight | 250.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-{[(2,2-dimethylpropyl)carbamoyl]amino}benzoic acid (CAS 1292367-49-7)
- 1-Boc-4,4-difluoropiperidine-3-methanamine (CAS 1303973-27-4)
- Methyl 3-amino-4-(((tetrahydrofuran-2-yl)methyl)amino)benzoate (CAS 1291986-37-2)
- 2-(cyclohexyloxy)-4-methoxybenzoic acid (CAS 1306075-87-5)
- 8-Methyl-6-chloroisoquinoline (CAS 196875-78-2)
- 2-(3-Bromophenyl)-2-oxoacetaldehyde hydrate (CAS 1172443-36-5)
- IWP-3 (CAS 687561-60-0)
- 0436AD 1185301-59-0 2-Ethylphenyl 4-piperidinyl ether hydrochloride C13H20ClNO (CAS 1185301-59-0)
- N-cyclohexyl-2-naphthamide (CAS 82740-60-1)
- Rifamdin (CAS 89499-17-2)
- 1,2,2-Trimethyl-3-(morpholine-4-carbonyl)cyclopentane-1-carboxylic acid (CAS 625823-17-8)
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- 3,5-Dibromo-4-ethylpyridin-2-amine (CAS 867131-58-6)
- Calcitonin C-Terminal Flanking Peptide (human) XTFA (CAS 85916-47-8（free base）)
Why CATO?
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