6-(4-(Trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole CAS 130598-74-2
| CAS No. | 130598-74-2 |
| Molecular Formula | C12H8F3N3 |
| Molecular Weight | 251.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-(4-(Trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole (CAS 130598-74-2) is a high-purity analytical reference standard with the molecular formula C12H8F3N3 and a molecular weight of 251.21 g/mol.
6-(4-(Trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole (C12H8F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F3N3 |
| Molecular Weight | 251.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 6-(3-(Trifluoromethyl)phenyl)-1H-imidazo[1,2-b]pyrazole (CAS 130598-75-3)
- (4-Trifluoromethyl-2H-pyrazol-3-yl)-carbamic acid tert-butyl ester (CAS 2355385-20-3)
- 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl propylcarbamate (CAS 477713-72-7)
- 2-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzonitrile (CAS 910037-17-1)
- 3-(5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzonitrile (CAS 209958-67-8)
- 8-Methyl-5-(3-(trifluoromethyl)-3H-diazirin-3-yl)quinoline (CAS 2231672-99-2)
- 4-(4-(Trifluoromethyl)phenyl)picolinaldehyde (CAS 1005189-47-8)
- 6-(2-(Trifluoromethyl)phenyl)picolinaldehyde (CAS 112432-96-9)
Recommended Standards
- ethyl 5-amino-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazole-4-carboxylate (CAS 1285486-92-1)
- 5-((4-Fluoro-2-nitrophenoxy)methyl)-1-methyl-1H-pyrazole (CAS 1245823-45-3)
- 2,2,2-trifluoroethyl 1-isopropyl-1H-pyrazol-5-ylcarbamate (CAS 1334023-30-1)
- 5-((2-Fluoro-4-nitrophenoxy)methyl)-1-methyl-1H-pyrazole (CAS 1245772-04-6)
- 5-(Azetidin-3-yl)-3-((4-methoxyphenoxy)methyl)-1,2,4-oxadiazole (CAS 1706443-27-7)
- n-Allyl-4-chloro-3-(methylsulfonyl)benzamide (CAS 852682-03-2)
- Methyl 2-formyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-4-carboxylate (CAS 885704-80-3)
- (R)-2-(4,5-dichloro-2-fluorophenyl)pyrrolidine (CAS 1381928-46-6)
- 4-Ethylisoxazole-5-carboxylic acid (CAS 1518161-26-6)
- 1-(1h-Pyrazol-1-yl)propan-2-one (CAS 64882-48-0)
- tert-Butyl 2,6-diazabicyclo[2.2.1]heptane-2-carboxylate (CAS 885269-12-5)
- 3-(2,3-Dioxoindolin-5-yl)benzonitrile (CAS 893736-51-1)
- 6-Amino-1-ethyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 15468-21-0)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com