2,2,2-Trifluoroethyl n-[2-chloro-5-(dimethylcarbamoyl)phenyl]carbamate CAS 1306605-69-5
| CAS No. | 1306605-69-5 |
| Molecular Formula | C12H12ClF3N2O3 |
| Molecular Weight | 324.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trifluoroethyl n-[2-chloro-5-(dimethylcarbamoyl)phenyl]carbamate.
2,2,2-Trifluoroethyl n-[2-chloro-5-(dimethylcarbamoyl)phenyl]carbamate (CAS 1306605-69-5), molecular formula C12H12ClF3N2O3 and molecular weight 324.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,2,2-Trifluoroethyl n-[2-chloro-5-(dimethylcarbamoyl)phenyl]carbamate (C12H12ClF3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 324.68 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2,2-Trifluoroethyl n-[2-chloro-5-(dimethylcarbamoyl)phenyl]carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12ClF3N2O3 |
| Molecular Weight | 324.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Trifluoroethyl Standards
- 2,2,2-trifluoroethyl N-(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)carbamate (CAS 1221725-15-0)
- 2,2,2-Trifluoroethyl n-{2-phenyl-2h,4h,5h,6h-cyclopenta[c]pyrazol-3-yl}carbamate (CAS 1354951-54-4)
- 2,2,2-Trifluoroethyl n-(3-{5h,6h,7h-pyrrolo[2,1-c][1,2,4]triazol-3-yl}phenyl)carbamate (CAS 1221725-30-9)
- 2,2,2-Trifluoroethyl (2,4,5-trichlorophenyl)carbamate (CAS 1087798-21-7)
- 2,2,2-Trifluoroethyl n-[3-(1-cyclopropyl-1h-1,2,3,4-tetrazol-5-yl)phenyl]carbamate (CAS 1221724-15-7)
- 2,2,2-Trifluoroethyl (3-((2-oxopyrimidin-1(2h)-yl)methyl)phenyl)carbamate (CAS 1221724-50-0)
- 2,2,2-Trifluoroethyl n-[4-(2-methyl-6-oxo-1,6-dihydropyrimidin-4-yl)phenyl]carbamate (CAS 1354950-25-6)
- 2,2,2-Trifluoroethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate (CAS 1087788-65-5)
Recommended Standards
- 4-(Aminomethyl)-6-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-sulfonyl chloride (CAS 1361887-11-7)
- Methyl 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-4-hydroxy-2-pyrrolidinecarboxylate (CAS 251097-80-0)
- 4-(Aminomethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-sulfonyl chloride (CAS 1361869-36-4)
- Azamethiphos (CAS 35575-96-3)
- 2-(5-Chloro-1H-indol-3-yl)-2-oxoacetyl chloride (CAS 883-55-6)
- 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylic acid (CAS 332099-11-3)
- Methyl 6-bromopyrimidine-4-carboxylate (CAS 1209459-80-2)
- 6'-(Trifluoromethyl)-2'H-spiro[azepane-4,3'-benzofuran]-7-one (CAS 2351201-11-9)
- 2-Amino-5-iodo-4-(trifluoromethyl)benzoic acid (CAS 1427400-33-6)
- 4-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 1234616-75-1)
- Ethyl 4-(4-methylpiperidin-1-yl)benzoate (CAS 1160246-03-6)
- Ethyl 4-chloro-5-(((2-hydroxyethyl)amino)methyl)-3-methylbenzofuran-2-carboxylate (CAS 356586-66-8)
- Ethyl 2-bromo-5-iodobenzoate (CAS 1208075-44-8)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
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