(4-Chloro-2-fluorophenyl)methanesulfonyl chloride CAS 1308384-53-3

Description

The occurrence of (4-Chloro-2-fluorophenyl)methanesulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(4-Chloro-2-fluorophenyl)methanesulfonyl chloride (CAS 1308384-53-3), molecular formula C7H5Cl2FO2S and molecular weight 243.08 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, (4-Chloro-2-fluorophenyl)methanesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (4-Chloro-2-fluorophenyl)methanesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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