Buspirone EP Impurity A-d8 (Buspirone USP Related Compound A-d8) CAS 1309283-31-5
| CAS No. | 1309283-31-5 |
| Molecular Formula | - |
| Molecular Weight | 172.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 172.26 g/mol gives Buspirone EP Impurity A-d8 (Buspirone USP Related Compound A-d8) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Buspirone EP Impurity A-d8 (Buspirone USP Related Compound A-d8) (CAS 1309283-31-5) is a certified pharmaceutical impurity reference standard with the molecular formula C8H4D8N4 and a molecular weight of 172.26 g/mol.
Buspirone EP Impurity A-d8 (Buspirone USP Related Compound A-d8) (C8H4D8N4) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4D8N4 |
| Molecular Weight | 172.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Buspirone Standards
- Buspirone Impurity 8 (CAS 5660-82-2)
- Buspirone Impurity N1 (CAS 5662-95-3)
- Buspirone EP Impurity K (CAS 1075-89-4)
- Buspirone EP Impurity A (CAS 20980-22-7)
- Buspirone Impurity 20 (CAS 1821194-01-7)
- Buspirone Impurity 14 (CAS 60143-00-2)
- Buspirone Impurity 42 (CAS CATO-C4X-125842)
- Buspirone Impurity 21 (CAS 137583-05-2)
Recommended Standards
- Neodecanoic acid (CAS 130776-67-9)
- (2,2,6,6-tetramethyloxan-4-yl)methanol (CAS 1314398-25-8)
- 2,2-Dimethyl-3-(tetrahydro-2h-pyran-4-yl)propan-1-ol (CAS 1262409-40-4)
- 2,2-Dimethyl-3-(2-methylpropoxy)cyclobutan-1-ol (CAS 1333695-19-4)
- Ribavirin EP Impurity D (CAS 3641-08-5)
- Perindopril Impurity 78 HCl (CAS CATO-C4X-125281)
- Pazopanib Impurity 45(Mixture of Isomers) (CAS CATO-C4X-172545)
- 2-Methylthiazole (CAS 3581-87-1)
- 3-Chloro-2-(3,3-difluorocyclobutyl)pyridine (CAS 1355070-38-0)
- 2-Deoxy-3,4:5,6-di-O-isopropylidene-D-arabino-hexose Propylene Dithioacetal (CAS 91294-64-3)
- n-(2-(Thiophen-2-yl)ethyl)cyclopentanamine (CAS 58924-76-8)
- (1R,4S)-5-tert-Butoxycarbonyl-2-oxa-5-azabicyclo[2.2.1]heptane-1-carboxylic acid (CAS 1932416-77-7)
- 2,5-Dioxopyrrolidin-1-yl 3-((2,4-difluorobenzyl)oxy)propanoate (CAS 1134280-65-1)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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