Pazopanib Impurity 45(Mixture of Isomers) CAS CATO-C4X-172545

Description

The occurrence of Pazopanib Impurity 45(Mixture of Isomers) is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Pazopanib Impurity 45(Mixture of Isomers) (CAS CATO-C4X-172545) is a certified pharmaceutical impurity reference standard with the molecular formula C7H4N4O3 and a molecular weight of 192.13 g/mol.

Based on its molecular formula C7H4N4O3, Pazopanib Impurity 45(Mixture of Isomers) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 192.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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