Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate CAS 1309439-45-9
| CAS No. | 1309439-45-9 |
| Molecular Formula | C13H16ClFN2O2 |
| Molecular Weight | 286.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate (C13H16ClFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate (CAS 1309439-45-9), a certified reference material (molecular formula C13H16ClFN2O2, MW 286.73 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16ClFN2O2 |
| Molecular Weight | 286.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- Methyl 3-chloro-4,5-dimethoxybenzo[b]thiophene-2-carboxylate (CAS 1171455-34-7)
- 2-Chloro-4-(2-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1225701-60-9)
- 2-Chloro-4-(4-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1225701-69-8)
- n-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-N-methylglycine (CAS 1352999-21-3)
- 2-Chloro-N-(3-fluoro-4-morpholinobenzyl)acetamide (CAS 1423024-98-9)
- 2-Chloro-4-(3-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1603053-64-0)
- (2-Chloro-4-fluoro-3-methoxyphenyl)(4-methylpiperazin-1-yl)methanone (CAS 2586126-49-8)
- 2-Chloro-3-formyl-N,N-dimethyl-1H-indole-5-sulfonamide (CAS 535925-58-7)
Recommended Standards
- Methyl 6-(chloromethyl)-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1260621-91-7)
- 2-(4-Fluorobenzenesulfonyl)ethane-1-sulfonyl chloride (CAS 1354951-80-6)
- 3-(Ethylsulfonyl)-4-fluorobenzenesulfonyl chloride (CAS 1354963-44-2)
- 3-Amino-4-chloro-N-(2-furylmethyl)-benzenesulfonamide (CAS 1036545-43-3)
- 1-(Bromomethyl)-1,4-difluorocyclohexane (CAS 2306268-31-3)
- 5-Chloro-2-fluoroiodobenzene (CAS 116272-42-5)
- 1,1,1-Trifluoro-2-isothiocyanatoethane (CAS 59488-39-0)
- (7aS)-6-Hydroxy-7a-(hydroxymethyl)-6-methylhexahydro-3H-pyrrolizin-3-one (CAS 2763158-13-8)
- 3-(2-Methyl-1H-imidazol-1-yl)aniline (CAS 184098-19-9)
- 6-Bromo-5-chloro-2-(difluoromethyl)pyridin-3-ol (CAS 1805087-99-3)
- 1-Aminonaphthalene (CAS 134-32-7)
- (R)-Methyl 2-hydroxy-3-(tetrahydro-2H-pyran-4-yl)propanoate (CAS 1207447-41-3)
- 4-Iodo-5-methoxynicotinotrile (CAS 1138444-07-1)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com