4-Chloro-N-[3-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide CAS 1311278-87-1
| CAS No. | 1311278-87-1 |
| Molecular Formula | C21H17ClF3N3O |
| Molecular Weight | 419.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-N-[3-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide (CAS 1311278-87-1) is a high-purity analytical reference standard with the molecular formula C21H17ClF3N3O and a molecular weight of 419.83 g/mol.
The molecular framework of 4-Chloro-N-[3-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide (C21H17ClF3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-N-[3-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17ClF3N3O |
| Molecular Weight | 419.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-N-[2-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide (CAS 1311278-03-1)
- 4-Chloro-N-[4-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-benzamide (CAS 1311278-32-6)
- N-(4-Chloro-phenyl)-4-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzamide (CAS 1311278-88-2)
- N-(4-Chloro-phenyl)-3-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzamide (CAS 1311279-60-3)
- 4-Chloro-N-[3-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-benzamide (CAS 1311279-66-9)
- 2-Chloro-N-[2-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-benzamide (CAS 1311279-93-2)
- 4-Chloro-N-[4-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide (CAS 1311280-15-5)
- 1024523-09-8 ((4-Chloro-3-nitrophenyl)sulfonyl)(3-(phenylmethoxy)(2-pyridyl))amine MFCD07777934 (CAS 1024523-09-8)
Recommended Standards
- (1E,4E)-1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-5-(dimethylamino)penta-1,4-dien-3-one (CAS 1164556-97-1)
- 1076235-04-5 PAW9EP9BXO CBS-9106 UNII-PAW9EP9BXO SL-801 1-((6-Chloro-5-(trifluoromethyl)-2-pyridinyl)amino)-3-((3,3-dimethylbutoxy)methyl)-4-methyl-1H-pyrrole-2,5-dione (CAS 1076235-04-5)
- N-(4-chloro-3-nitrophenyl)-2-(4-(4-nitrophenyl)piperazin-1-yl)acetamide (CAS 892158-25-7)
- 2-Chloro-5-nitro-N-(4-(quinolin-2-yloxy)phenyl)benzamide (CAS 647852-85-5)
- 2-(1-methyl-1H-imidazol-2-yl)piperazine trihydrochloride (CAS 1798700-80-7)
- (7R,8aR)-7-fluorohexahydropyrrolo[1,2-a]pyrazin-1(2H)-one (CAS 2165895-50-9)
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- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
Why CATO?
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