4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-(4-chlorophenyl)piperazine-1-carboxamide CAS 1311279-57-8
| CAS No. | 1311279-57-8 |
| Molecular Formula | C18H17Cl2F3N4O |
| Molecular Weight | 433.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-(4-chlorophenyl)piperazine-1-carboxamide (CAS 1311279-57-8), a certified reference material (molecular formula C18H17Cl2F3N4O, MW 433.25 g/mol) for analytical method development and quality control.
4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-(4-chlorophenyl)piperazine-1-carboxamide (C18H17Cl2F3N4O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17Cl2F3N4O |
| Molecular Weight | 433.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- (2-(3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)thiazol-5-yl)(4-chlorophenyl)methanone (CAS 339276-60-7)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-cyanopropan-2-yl N-(4-chlorophenyl)carbamate (CAS 338399-88-5)
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- 3-(6-Chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-4-methylbenzoic acid (CAS 1415564-64-5)
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Recommended Standards
- 6-Iodo-4-(3-methoxyphenylamino)-8-methylquinoline-3-carboxamide (CAS 807325-83-3)
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- 4-{[(E)-2-[3-(2,6-dichlorophenyl)-4-(methoxycarbonyl)-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid (CAS 338394-43-7)
- Perfluorophenyl 4-(5-(trifluoromethyl)pyridin-2-yl)benzoate (CAS 910036-89-4)
- (S)-1-(4-Chlorophenyl)-2-methylpropan-1-amine (CAS 82776-23-6)
- 3-Chloro-5-(fluoromethoxy)picolinonitrile (CAS 1262860-71-8)
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- 8-Bromo-5-hydroxy-4-(2-hydroxyethyl)quinolin-2-one (CAS 1155270-69-1)
- Methyl (2S,4S)-4-(2,4-dibromophenoxy)-2-pyrrolidinecarboxylate hydrochloride (CAS 1354487-21-0)
- 4-Acetamidophenyl Glycidyl Ether (CAS 6597-75-7)
- 1,1,1,2,2,6,6,7,7,7-Decafluoro-5-hydroxy-5-methylheptan-3-one (CAS 6742-92-3)
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- 2-Hydroxyquinoline (CAS 59-31-4)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
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