4-{[(E)-2-[3-(2,6-dichlorophenyl)-4-(methoxycarbonyl)-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid CAS 338394-43-7
| CAS No. | 338394-43-7 |
| Molecular Formula | C20H14Cl2N2O5 |
| Molecular Weight | 433.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-{[(E)-2-[3-(2,6-dichlorophenyl)-4-(methoxycarbonyl)-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid (CAS 338394-43-7) is a high-purity analytical reference standard with the molecular formula C20H14Cl2N2O5 and a molecular weight of 433.24 g/mol.
4-{[(E)-2-[3-(2,6-dichlorophenyl)-4-(methoxycarbonyl)-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid (C20H14Cl2N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H14Cl2N2O5 |
| Molecular Weight | 433.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (E)-[(2,6-Dichlorophenyl)methoxy]({[3-nitro-4-(phenylsulfanyl)phenyl]methylidene})amine (CAS 477852-26-9)
- N-(3,5-Dichlorophenyl)-2-[(6-acetamidopyridin-3-yl)sulfanyl]pyridine-3-carboxamide (CAS 343373-16-0)
- 2-(((3,4-Dichlorophenyl)methyl)amino)-1,7-dihydro-7-(2-(4-morpholinyl)ethyl)-6H-purin-6-one (CAS 1275582-97-2)
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- 2-(3,5-Dichlorophenyl)-4-methyl-6-(2-(pyridin-3-yl)thiazol-4-yl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 477854-33-4)
- Methyl 4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoate (CAS 864736-32-3)
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Recommended Standards
- 1-(5-(Benzyloxy)-2,4-dichlorophenyl)-5-(2,6-difluorophenyl)-1H-tetrazole (CAS 338961-50-5)
- 6-Iodo-4-(3-methoxyphenylamino)-8-methylquinoline-3-carboxamide (CAS 807325-83-3)
- [4-(4-Chlorophenoxy)-3-nitrophenyl]methyl N-(3-chlorophenyl)carbamate (CAS 339279-24-2)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-(4-chlorophenyl)piperazine-1-carboxamide (CAS 1311279-57-8)
- (5-Chloro-2-methoxy-4-methylphenyl)acetic acid (CAS 383134-15-4)
- (2R,3S)-3-(Piperidin-1-ylmethyl)oxirane-2-carboxylic acid (CAS 1208067-16-6)
- 5-Norbornene-2-acetic acid succinimidyl ester (CAS 1234203-45-2)
- 5-(2-Hydroxyethyl)pyrrolidin-2-one (CAS 149427-84-9)
- N-(2,5-Difluorobenzyl)-3-methoxy-1-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1856065-76-3)
- 2,2,6,6-Tetrafluoromorpholine hydrochloride (CAS 1193388-15-6)
- 4-Benzyl-2-methylmorpholine-3-carboxylic acid (CAS 1496493-00-5)
- (5-Cyano-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid (CAS 56673-29-1)
- 4-(2-Ethyl-6-hydroxypyrimidin-4-yl)-1-methylpyrrolidin-2-one (CAS 1707386-78-4)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
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