1-(2-chloroacetyl)-N-methyl-N-(propan-2-yl)piperidine-4-carboxamide CAS 1311314-48-3
| CAS No. | 1311314-48-3 |
| Molecular Formula | C12H21ClN2O2 |
| Molecular Weight | 260.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-chloroacetyl)-N-methyl-N-(propan-2-yl)piperidine-4-carboxamide.
CATO supplies 1-(2-chloroacetyl)-N-methyl-N-(propan-2-yl)piperidine-4-carboxamide (CAS 1311314-48-3), a certified reference material (molecular formula C12H21ClN2O2, MW 260.76 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-chloroacetyl)-N-methyl-N-(propan-2-yl)piperidine-4-carboxamide (C12H21ClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2-chloroacetyl)-N-methyl-N-(propan-2-yl)piperidine-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H21ClN2O2 |
| Molecular Weight | 260.76 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloroacetyl Standards
- N-((1-(2-Chloroacetyl)piperidin-2-yl)methyl)-N-ethylacetamide (CAS 1353952-27-8)
- N-((1-(2-Chloroacetyl)pyrrolidin-3-yl)methyl)-N-isopropylacetamide (CAS 1353958-10-7)
- N-((1-(2-Chloroacetyl)pyrrolidin-2-yl)methyl)-N-isopropylacetamide (CAS 1353968-63-4)
- N-((1-(2-Chloroacetyl)piperidin-3-yl)methyl)-N-ethylacetamide (CAS 1353972-95-8)
- N-((1-(2-Chloroacetyl)piperidin-4-yl)methyl)-N-ethylacetamide (CAS 1353983-09-1)
- n'-(2-Chloroacetyl)-5-ethyl-4-methylthiophene-2-carbohydrazide (CAS 1334146-63-2)
- n'-(2-Chloroacetyl)-4-ethyl-5-methylthiophene-2-carbohydrazide (CAS 794582-33-5)
- Methyl β-[(2-chloroacetyl)amino]-2-thiophenepropanoate (CAS 1153928-34-7)
Recommended Standards
- 3-Chloro-1-(4-((tetrahydrofuran-2-yl)methyl)piperazin-1-yl)propan-1-one (CAS 1178838-61-3)
- 2-Chloro-N-(2-(N-ethylacetamido)cyclohexyl)acetamide (CAS 1353943-52-8)
- (S)-3-Chloro-1-phenyl-1-[2-methyl-phenoxyl]propane (CAS 114446-50-3)
- 2-Chloro-N-(4-(N-ethylacetamido)cyclohexyl)acetamide (CAS 1353946-96-9)
- 5-Bromo-2-pyrimidinylacetic Acid (CAS 1134327-93-7)
- cis-1,2-Cyclopentanediol 5057-98-7 cis-1,2-Dihydroxycyclopentane (CAS 5057-98-7)
- Ethyl 2-phenylimidazo[1,2-a]pyrimidine-3-carboxylate (CAS 127801-89-2)
- 2-[4-chloro-5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl]propanoic acid (CAS 1005679-11-7)
- 3-Amino-1-(pyridin-3-yl)thiourea (CAS 34955-25-4)
- 2-Bromo-3-cyclopropoxyisonicotinamide (CAS 1243354-55-3)
- N-(Thiazol-2-yl)picolinamide (CAS 301208-58-2)
- N-(3-chlorophenyl)-4-(2-chloropyridin-4-yl)-1,3,5-triazin-2-amine (CAS 652153-37-2)
- rac-Lasofoxifene (CAS 180915-78-0)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
Why CATO?
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