3-(1,1-Difluoroethyl)-3-Methyloxolan-2-One CAS 131147-39-2
| CAS No. | 131147-39-2 |
| Molecular Formula | C7H10F2O2 |
| Molecular Weight | 164.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(1,1-Difluoroethyl)-3-Methyloxolan-2-One (CAS 131147-39-2) is a high-purity analytical reference standard with the molecular formula C7H10F2O2 and a molecular weight of 164.15 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 3-(1,1-Difluoroethyl)-3-Methyloxolan-2-One is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 164.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(1,1-Difluoroethyl)-3-Methyloxolan-2-One meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F2O2 |
| Molecular Weight | 164.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related Difluoroethyl Standards
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- methyl 1-(1,1-difluoroethyl)cyclopropane-1-carboxylate (CAS 1909319-67-0)
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- 4-(1,1-Difluoroethyl)cyclohexan-1-ol (CAS 1379340-14-3)
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Recommended Standards
- 2,4,6-Trifluorobenzene-1-thiol (CAS 130922-42-8)
- Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers) (CAS 132523-94-5)
- Ethyl 1-(difluoromethyl)cyclopropane-1-carboxylate (CAS 1267856-62-1)
- (1R,3S,4R)-3,4-difluorocyclohexane-1-carboxylic acid (CAS 1346604-76-9)
- 2-Ethyl-6-Methylaniline (CAS 24549-06-2)
- 5-(2,2,2-Trifluoroacetamido)pentanoic acid (CAS 50632-84-3)
- 2-((1S,4s)-4-hydroxycyclohexyl)acetic acid (CAS 68592-22-3)
- (S)-4-(Pyrrolidin-2-yl)pyridine (CAS 130343-14-5)
- tert-Butyl 6-amino-7-cyano-2,3-dihydro-1H-pyrrolizine-5-carboxylate (CAS 1708079-62-2)
- (S)-methyl 2-(3-chlorophenyl)-2-hydroxyacetate (CAS 32222-44-9)
- 2-(2-Chlorophenyl)-4h-benzo[d][1,3]oxazin-4-one (CAS 4765-51-9)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-(trifluoromethoxy)pyridine-5-acetonitrile (CAS 1806779-21-4)
- 2-(3-Bromobenzenesulfonyl)ethanol (CAS 1021169-75-4)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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