Glycopyrronium Bromide EP Impurity G CAS 13118-11-1
| CAS No. | 13118-11-1 |
| Molecular Formula | C18H25NO3 |
| Molecular Weight | 303.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Glycopyrronium Bromide EP Impurity G (CAS 13118-11-1), a pharmacopoeial impurity reference standard (molecular formula C18H25NO3, MW 303.40 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Glycopyrronium Bromide EP Impurity G (C18H25NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H25NO3 |
| Molecular Weight | 303.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 1 |
Related Glycopyrronium Standards
- Glycopyrronium Bromide Impurity 13 (CAS CATO-C4X-181713)
- Glycopyrronium Bromide Impurity 9 (CAS CATO-C4X-18179)
- Glycopyrronium Bromide Impurity N1 (CAS 13283-82-4)
- Glycopyrronium Bromide impurity 17 (CAS CATO-C4X-181717)
- Glycopyrronium Bromide Impurity 22 (CAS CATO-C4X-181722)
- Glycopyrronium Bromide impurity 16 (CAS 16098-80-9)
- Glycopyrronium Bromide EP Impurity L (CAS 64471-47-2)
- Glycopyrronium Bromide EP Impurity L (CAS 19833-96-6)
Recommended Standards
- Nateglinide EP Impurity E (CAS 105746-45-0)
- Lafutidine Impurity 11 (CAS 154923-16-7)
- Vildagliptin Impurity 87 (CAS 1789703-37-2)
- Cyproheptadine impurity 14 (CAS 34663-46-2)
- Ertugliflozin Impurity 2 (CAS CATO-C4X-30112)
- Bumetanide Impurity 114 (CAS CATO-C4X-1986114)
- Umeclidinium Impurity 4 (CAS 869112-31-2)
- Methyl 8-chlorooctanoate (CAS 16195-75-8)
- 4-Methyl-1,5-dihydro-2H-pyrrol-2-one (CAS 53598-99-5)
- 2-(Isopropyl(methyl)amino)ethyl 3-fluorobenzoate (CAS 425649-98-5)
- Cyclophosphamide impurity 31 (CAS 2517939-95-4(free base))
- a,a-Dicyclohexyl-2-pyridineethanol (CAS 102658-00-4)
- 1-(2-(Pyridin-2-yl)ethyl)-1h-tetrazole-5-thiol (CAS 1038377-20-6)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com