Methyl 4-bromo-8-fluoroquinoline-2-carboxylate CAS 1314141-67-7
| CAS No. | 1314141-67-7 |
| Molecular Formula | C11H7BrFNO2 |
| Molecular Weight | 284.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-bromo-8-fluoroquinoline-2-carboxylate.
CATO supplies Methyl 4-bromo-8-fluoroquinoline-2-carboxylate (CAS 1314141-67-7), a certified reference material (molecular formula C11H7BrFNO2, MW 284.08 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 4-bromo-8-fluoroquinoline-2-carboxylate (C11H7BrFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 4-bromo-8-fluoroquinoline-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7BrFNO2 |
| Molecular Weight | 284.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 4-Bromo-6-fluoro-8-methylquinoline-3-carboxylic acid (CAS 1378259-52-9)
- 8-Bromo-6-fluoro-7-methylquinoline-2-carboxylic acid (CAS 1420791-61-2)
- 5-Bromo-6-fluoro-8-methylquinoline-2-carboxylic acid (CAS 1420792-15-9)
- 8-Bromo-6-fluoro-7-methylquinoline-4-carboxylic acid (CAS 1420792-30-8)
- 5-Bromo-8-fluoro-6-methylquinoline-2-carboxylic acid (CAS 1420794-38-2)
- Methyl 5-bromo-4-sulfamoylfuran-2-carboxylate (CAS 1494621-26-9)
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Recommended Standards
- Crisaborole lmpurity 89 (CAS 1187187-13-8)
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- Des-Phe22-Tirzepatide (CAS CATO-CPTD788951)
Why CATO?
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