2-((5-Chloro-8-methoxyquinolin-4-yl)thio)acetic acid CAS 1315349-45-1
| CAS No. | 1315349-45-1 |
| Molecular Formula | C12H10ClNO3S |
| Molecular Weight | 283.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-((5-Chloro-8-methoxyquinolin-4-yl)thio)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-((5-Chloro-8-methoxyquinolin-4-yl)thio)acetic acid (CAS 1315349-45-1) is a high-purity analytical reference standard with the molecular formula C12H10ClNO3S and a molecular weight of 283.73 g/mol.
2-((5-Chloro-8-methoxyquinolin-4-yl)thio)acetic acid (C12H10ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO3S |
| Molecular Weight | 283.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-((5-Chloro-1,3,4-thiadiazol-2-yl)oxy)-N-methyl-N-phenylacetamide (CAS 105609-61-8)
- 2-Chloro-N-(5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 1105192-65-1)
- 4-Chloro-6-(methanesulfonylmethyl)-2-(pyridin-3-yl)pyrimidine (CAS 1610377-09-7)
- 2-(3-Chloro-phenoxy)-thiazole-4-carboxylic acid ethyl ester (CAS 162276-40-6)
- 2-Chloro-N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 18199-99-0)
- (Z)-({2-[(5-chloro-1,2,3-thiadiazol-4-yl)methoxy]phenyl}methylidene)(methoxy)amine (CAS 338954-28-2)
- 2-{[4-(3-chloro-4-methylphenyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 923713-39-7)
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Recommended Standards
- 4-(2-Cyclopropyloxazol-5-yl)benzenesulfonyl chloride (CAS 1279219-24-7)
- Ethyl 2-(3-chlorophenyl)-4-hydroxythiazole-5-carboxylate (CAS 144060-65-1)
- N-(4-(6-chloropyridazin-3-yl)phenyl)methanesulfonamide (CAS 1262619-30-6)
- Methyl (3-chlorobenzo[b]thiophene-2-carbonyl)glycinate (CAS 144936-71-0)
- (1R,2S,3S,5S)-3-(4-Iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid (CAS 141807-58-1)
- 3-Vinyl-quinoline (CAS 67752-31-2)
- 5-Chloro-6-ethyl-N-(1-(naphthalen-2-yl)ethyl)pyrimidin-4-amine (CAS 141601-05-0)
- Afoxolaner impurity 4 (CAS CATO-C4X-31374)
- Dimethyl 3-(Benzylamino)glutarate, 97% (CAS 109270-76-0)
- 2-Formylphenyl 4-methylbenzenesulfonate (CAS 19820-56-5)
- (R)-Tetrahydrofuran-2-carbaldehyde (CAS 22170-11-2)
- 3-(4-Chlorophenyl)-1-methyl-5-(methylsulfonyl)-1H-1,2,4-triazole (CAS 154106-11-3)
- 4-(1-Acetyl-piperazin-2-yl)-benzoic acid methyl ester (CAS 1316218-72-0)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
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