2-(3-Chloro-phenoxy)-thiazole-4-carboxylic acid ethyl ester CAS 162276-40-6
| CAS No. | 162276-40-6 |
| Molecular Formula | C12H10ClNO3S |
| Molecular Weight | 283.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(3-Chloro-phenoxy)-thiazole-4-carboxylic acid ethyl ester (CAS 162276-40-6), molecular formula C12H10ClNO3S and molecular weight 283.73 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H10ClNO3S, 2-(3-Chloro-phenoxy)-thiazole-4-carboxylic acid ethyl ester contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 283.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO3S |
| Molecular Weight | 283.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 2-Chloro-N-(5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 1105192-65-1)
- 2-((5-Chloro-8-methoxyquinolin-4-yl)thio)acetic acid (CAS 1315349-45-1)
- 4-Chloro-6-(methanesulfonylmethyl)-2-(pyridin-3-yl)pyrimidine (CAS 1610377-09-7)
- 2-Chloro-N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 18199-99-0)
- (Z)-({2-[(5-chloro-1,2,3-thiadiazol-4-yl)methoxy]phenyl}methylidene)(methoxy)amine (CAS 338954-28-2)
- 2-{[4-(3-chloro-4-methylphenyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 923713-39-7)
- 2-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde (CAS 955978-98-0)
Recommended Standards
- 4-(4-Chlorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 1707379-61-0)
- Methyl (3-chlorobenzo[b]thiophene-2-carbonyl)glycinate (CAS 144936-71-0)
- 4-(3-Chlorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 1708179-35-4)
- Ethyl 2-(3-chlorophenyl)-4-hydroxythiazole-5-carboxylate (CAS 144060-65-1)
- Sulfacetamide-13C6 (CAS CATO-CCAD301374)
- Benzyl 2-((2-aminoethoxy)methyl)pyrrolidine-1-carboxylate (CAS 1353980-86-5)
- 4-(2-Chloro-5-(trifluoromethyl)phenyl)pyridine (CAS 4393-93-5)
- (1-Bromocyclopropyl)methanamine hydrochloride (CAS 2413870-45-6)
- 2-Chloro-7-nitroquinazoline (CAS 2203445-31-0)
- Harmalidine (CAS 109794-97-0)
- 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline (CAS 937263-71-3)
- 2-Chloro-6-(hydroxymethyl)phenol (CAS 22471-02-9)
- Methanesulfonylmethyl-carbamic acid tert-butyl ester (CAS 1555965-44-0)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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