6-(Trifluoromethyl)pyridine-2-carboxaldehyde CAS 131747-65-4
| CAS No. | 131747-65-4 |
| Molecular Formula | C7H10F3NO |
| Molecular Weight | 181.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(Trifluoromethyl)pyridine-2-carboxaldehyde is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(Trifluoromethyl)pyridine-2-carboxaldehyde (CAS 131747-65-4), molecular formula C7H10F3NO and molecular weight 181.16 g/mol, is a CATO reference standard with documented purity and traceability.
6-(Trifluoromethyl)pyridine-2-carboxaldehyde (C7H10F3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(Trifluoromethyl)pyridine-2-carboxaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F3NO |
| Molecular Weight | 181.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 2-(trifluoromethyl)pyridine-4-carbaldehyde (CAS 108338-20-1)
- 6-(Trifluoromethyl)-3-azabicyclo[3.1.1]heptan-6-ol (CAS 1240525-82-9)
- 6-(Trifluoromethyl)-2-azaspiro[3.3]heptan-6-ol (CAS 1251924-12-5)
- (4-(Trifluoromethyl)-2-azabicyclo[2.1.1]hexan-1-yl)methanol (CAS 2639439-88-4)
- (4-(Trifluoromethyl)-2-oxabicyclo[2.1.1]hexan-1-yl)methanamine (CAS 2361635-48-3)
- 6-methyl-4-(trifluoromethyl)-1H-pyridin-2-one (CAS 22123-19-9)
- 2-Trifluoromethyl-4-thiazolecarboxaldehyde (CAS 133046-48-7)
- 5-(Trifluoromethyl)thiazole-2-carbaldehyde (CAS 1379174-19-2)
Recommended Standards
- 1-(5-Fluoropyridin-2-yl)cyclopropanecarboxylic acid (CAS 1302580-98-8)
- (2S)-6-Fluoro-2,3-dihydro-1H-indole-2-carboxylic acid (CAS 1344411-42-2)
- 4-(3,3,3-Trifluoropropyl)pyrrolidin-2-one (CAS 1294000-91-1)
- D-Glucose-5-C-d (CAS 136864-16-9)
- 2-(Cyclopropylmethyl)-5-hydroxybenzonitrile (CAS 1243411-09-7)
- 1,1'-(Bicyclo[1.1.1]pentane-1,3-diyl)diethanone (CAS 115913-30-9)
- 3-Amino-1-methyl-5-(propylthio)-1H-pyrazole-4-carbonitrile (CAS 512845-55-5)
- GSK-2269557 (CAS 1254036-77-5)
- 2-Amino-N-(3,4-dimethylphenyl)acetamide hydrochloride (CAS 117044-51-6)
- 2-((4-(3-Nitrophenyl)thiazol-2-yl)methyl)thiazol-4-ol (CAS 860651-32-7)
- Ethyl (2e)-2-cyano-3-[(pyrazin-2-yl)amino]prop-2-enoate (CAS 871926-02-2)
- Cyclizine-d3 (N-methyl-d3) (CAS 1170155-67-5)
- 5-(Trifluoromethyl)-1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazole-4-carboxylic acid (CAS 1013794-64-3)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
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