6-methyl-4-(trifluoromethyl)-1H-pyridin-2-one CAS 22123-19-9
| CAS No. | 22123-19-9 |
| Molecular Formula | C7H10F3NO |
| Molecular Weight | 181.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-methyl-4-(trifluoromethyl)-1H-pyridin-2-one (C7H10F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 6-methyl-4-(trifluoromethyl)-1H-pyridin-2-one (CAS 22123-19-9), a certified reference material (molecular formula C7H10F3NO, MW 181.16 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-methyl-4-(trifluoromethyl)-1H-pyridin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F3NO |
| Molecular Weight | 181.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related methyl Standards
- 2-(trifluoromethyl)pyridine-4-carbaldehyde (CAS 108338-20-1)
- 6-(Trifluoromethyl)-3-azabicyclo[3.1.1]heptan-6-ol (CAS 1240525-82-9)
- 6-(Trifluoromethyl)-2-azaspiro[3.3]heptan-6-ol (CAS 1251924-12-5)
- 6-(Trifluoromethyl)pyridine-2-carboxaldehyde (CAS 131747-65-4)
- (4-(Trifluoromethyl)-2-azabicyclo[2.1.1]hexan-1-yl)methanol (CAS 2639439-88-4)
- (4-(Trifluoromethyl)-2-oxabicyclo[2.1.1]hexan-1-yl)methanamine (CAS 2361635-48-3)
- 2-Trifluoromethyl-4-thiazolecarboxaldehyde (CAS 133046-48-7)
- 5-(Trifluoromethyl)thiazole-2-carbaldehyde (CAS 1379174-19-2)
Recommended Standards
- 6-Fluoro-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 925005-78-3)
- 7-fluoro-2,3,4,5-tetrahydro-1,4-benzoxazepin-5-one (CAS 874767-62-1)
- 6-Fluoro-2,3-dihydro-1h-indole-2-carboxylic acid (CAS 899825-90-2)
- 8-Fluoro-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (CAS 844648-10-8)
- Benzyl trimethylammonium hexafluorophosphate (CAS 6427-70-9)
- N1-(4-(1,1-Dioxidoisothiazolidin-2-yl)phenyl)-N2-propyloxalamide (CAS 1105205-23-9)
- 1-(4-Amino-3-fluorophenyl)pyrrolidin-2-one (CAS 927870-59-5)
- Ethyl 6-oxodecanoate (CAS 4144-61-0)
- 4-(3,5-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326814-28-1)
- N-(piperidin-4-yl)tetrahydro-2H-pyran-4-carboxamide (CAS 1097781-67-3)
- 3-Hydroxy-2-(3-methoxyphenyl)-4H-chromen-4-one (CAS 76666-32-5)
- 2-Butoxynicotinaldehyde (CAS 1694428-67-5)
- 1-(1,1-Difluoroethyl)-2,4-dimethylbenzene (CAS 1204295-93-1)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com