Cefamandole Nafate EP Impurity D CAS 13183-79-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.13183-79-4
Molecular FormulaC2H4N4S
Molecular Weight116.14 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cefamandole Nafate EP Impurity D CAS 13183-79-4 chemical structure

Description

As a process- or degradation-related impurity, Cefamandole Nafate EP Impurity D (CAS 13183-79-4, C2H4N4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Structurally, Cefamandole Nafate EP Impurity D (C2H4N4S) contains a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 116.14 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC2H4N4S
Molecular Weight116.14 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1960
Nitrogen Atoms4
Sulfur Atoms1

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