Lacosamide EP Impurity D HCl (R-isomer) CAS 1322062-76-9
| CAS No. | 1322062-76-9 |
| Molecular Formula | C11H16N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lacosamide EP Impurity D HCl (R-isomer) (CAS 1322062-76-9, C11H16N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lacosamide EP Impurity D HCl (R-isomer) (C11H16N2O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lacosamide EP Impurity D HCl (R-isomer) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O2 HCl |
| Molecular Weight | 244.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lacosamide Standards
- Lacosamide EP Impurity J (CAS 100-46-9)
- Lacosamide-d3 (CAS 1217689-95-6)
- Lacosamide Impurity 14 (CAS 1219042-50-8)
- Lacosamide Impurity 46 (CAS 1253790-25-8)
- Lacosamide EP Impurity B (R-Isomer) (CAS 1318777-54-6)
- Lacosamide Impurity 9 (CAS 1318777-56-8)
- Lacosamide EP Impurity E Hcl (R-Isomer) (CAS 1322062-75-8)
- Lacosamide EP Impurity D Oxalate (CAS 1379592-19-4)
Recommended Standards
- Rupatadine impurity 11 (CAS CATO-C4X-102711)
- Dapagliflozin Impurity 167 (CAS CATO-C4X-1138167)
- Levonorgestrel Impurity 42 (CAS 62298-52-6)
- 6,8-Dichloropyrido[2,3-b]pyrazine (CAS 1283075-60-4)
- (R)-6-Oxaspiro[4.5]decan-9-amine (CAS 2382349-06-4)
- 2-([1,1'-Biphenyl]-4-yloxy)-1-amino-4-bromoanthracene-9,10-dione (CAS 923291-31-0)
- Clevidipine Impurity 36 (CAS CATO-C4X-101536)
- 3-(aminomethyl)-4-methoxyaniline hydrochloride (CAS 1864073-28-8)
- 1-(1-Isobutyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1707603-46-0)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com