Lacosamide EP Impurity E Hcl (R-Isomer) CAS 1322062-75-8
| CAS No. | 1322062-75-8 |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lacosamide EP Impurity E Hcl (R-Isomer).
As a process- or degradation-related impurity, Lacosamide EP Impurity E Hcl (R-Isomer) (CAS 1322062-75-8, C10H14N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lacosamide EP Impurity E Hcl (R-Isomer) (C10H14N2O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lacosamide EP Impurity E Hcl (R-Isomer) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O2 HCl |
| Molecular Weight | 230.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lacosamide Standards
- Lacosamide EP Impurity J (CAS 100-46-9)
- Lacosamide-d3 (CAS 1217689-95-6)
- Lacosamide Impurity 14 (CAS 1219042-50-8)
- Lacosamide Impurity 46 (CAS 1253790-25-8)
- Lacosamide EP Impurity B (R-Isomer) (CAS 1318777-54-6)
- Lacosamide Impurity 9 (CAS 1318777-56-8)
- Lacosamide EP Impurity D HCl (R-isomer) (CAS 1322062-76-9)
- Lacosamide EP Impurity D Oxalate (CAS 1379592-19-4)
Recommended Standards
- Dutasteride EP Impurity I (CAS 1648593-70-7)
- Betamethasone Impurity 122 (CAS CATO-C4X-1437122)
- Lumateperone Impurity 16 (CAS CATO-C4X-22016)
- Ethyl 1,2,3,4-tetrahydroquinoline-5-carboxylate (CAS 118128-78-2)
- N-Boc-2-Amino-3-quinolin-4-yl-propionic acid (CAS 1219149-34-4)
- Methyl 6-hydroxyquinoline-8-carboxylate (CAS 1261813-51-7)
- n-(4-Bromo-2-methylphenyl)methanesulfonamide (CAS 330468-71-8)
- 5-Chloro-6-methyl-2,3-dihydro-1H-inden-1-one (CAS 337507-82-1)
- 5-Bromo-1-isopropyl-1H-imidazole (CAS 1378632-40-6)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com