Diclazuril EP Impurity E CAS 132252-58-5
| CAS No. | 132252-58-5 |
| Molecular Formula | C14H9Cl3N2 |
| Molecular Weight | 311.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Diclazuril EP Impurity E (C14H9Cl3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 311.59 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Diclazuril EP Impurity E (CAS 132252-58-5) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9Cl3N2 and a molecular weight of 311.59 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Diclazuril EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl3N2 |
| Molecular Weight | 311.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Diclazuril Standards
- Diclazuril EP Impurity F (CAS 133648-80-3)
- Diclazuril (CAS 101831-37-2)
- Diclazuril-d4 (CAS 1632495-80-7)
- Diclazuril-13C3,15N2 (CAS CATO-CCAD302513)
- Diclazuril-methyl (CAS 103337-71-9)
- Diclazuril 6-Carboxamide (CAS 1797132-12-7)
- Diclazuril 6-Carboxylic Acid (CAS 862243-46-7)
- Diclazuril Impurity G (CAS 1798004-50-8)
Recommended Standards
- Cabazitaxel Impurity 37 (CAS 131023-37-5)
- (E)-1-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one (CAS 133031-38-6)
- (2E)-3-(2-Chlorophenyl)-1-(3,4-dichlorophenyl)prop-2-en-1-one (CAS 1208985-99-2)
- (2E)-3-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)prop-2-en-1-one (CAS 166824-09-5)
- Apremilast impurity 91 HCl (CAS 311310-97-1)
- Levosimendan Impurity 56 (CAS CATO-C4X-130856)
- Pefloxacin Impurity 8 (CAS CATO-C4X-23338)
- 3,9-Diazaspiro[5.5]Undecane dihydrochloride (CAS 2089256-14-2)
- 4-Chloro-2-(difluoromethyl)-5-(hydroxymethyl)nicotinonitrile (CAS 1806968-44-4)
- Ethyl 2-benzoyl-3-((ethoxycarbonyl)amino)-1H-indole-1-carboxylate (CAS 882864-43-9)
- (S)-4-Cyclohexyl-2-(pyridin-2-yl)-4,5-dihydrooxazole (CAS 192318-04-0)
- 5-Cyclopropyl-N-methyl-1,3,4-thiadiazol-2-amine (CAS 1225737-22-3)
- Benzyl (3-hydroxy-2,2-dimethylcyclobutyl)carbamate (CAS 1593474-15-7)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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