5-Chloro-2-((trimethylsilyl)ethynyl)pyridine CAS 132308-18-0
| CAS No. | 132308-18-0 |
| Molecular Formula | C10H12ClNSi |
| Molecular Weight | 209.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-Chloro-2-((trimethylsilyl)ethynyl)pyridine (CAS 132308-18-0), molecular formula C10H12ClNSi and molecular weight 209.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-2-((trimethylsilyl)ethynyl)pyridine (C10H12ClNSi) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNSi |
| Molecular Weight | 209.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1034467-33-8 4-Chloro-3-((trimethylsilyl)ethynyl)pyridine 7779AC C10H12ClNSi (CAS 1034467-33-8)
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