Coclaurine Impurity 2 HCl CAS 13233-00-6
| CAS No. | 13233-00-6 |
| Molecular Formula | C19H21NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Coclaurine Impurity 2 HCl (C19H21NO3HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Coclaurine Impurity 2 HCl (CAS 13233-00-6), a pharmacopoeial impurity reference standard (molecular formula C19H21NO3HCl, MW 347.84 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Coclaurine Impurity 2 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21NO3 HCl |
| Molecular Weight | 347.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Coclaurine Standards
- Coclaurine Impurity 112 (CAS 116331-72-7)
- Coclaurine Related Compound 1 (CAS 138644-99-2)
- (±)-Coclaurine HCl (CAS 17934-80-4)
- (R)-Coclaurine HCl (CAS 19894-19-0)
- Coclaurine Impurity 113 (CAS 2158198-78-6(TFA Salt))
- Coclaurine Impurity 111 (CAS 2158201-34-2(TFA Salt))
- (+)-Coclaurine (CAS 2196-60-3)
- Coclaurine Impurity 114 (CAS 31804-74-7)
Recommended Standards
- Ceftolozane Impurity 27 (CAS CATO-C4X-240627)
- Desvenlafaxine Impurity 5 (CAS CATO-C4X-16105)
- Budesonide Impurity 14 (CAS 5541-37-7)
- Ethyl 3,6-dipentyl-3,6-dihydro-2H-thiopyran-2-carboxylate (CAS 176495-35-5)
- Cryptotanshinone (CAS 35825-57-1)
- Tert-butyl (2-(5-methyl-1H-indol-3-yl)ethyl)carbamate (CAS 1228552-55-3)
- 2-Amino-1-(1-methyl-1,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)ethan-1-one (CAS 1443287-31-7)
- 2-[(tert-Butoxy)carbonyl]-5-oxa-2-azaspiro[3.4]octane-6-carboxylic acid (CAS 1251006-00-4)
- 5-Hydroxy-6-oxo-1,6-dihydropyridine-3-carboxylic Acid (CAS 76470-35-4)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com