Coclaurine Impurity 114 CAS 31804-74-7
| CAS No. | 31804-74-7 |
| Molecular Formula | C18H21NO3 |
| Molecular Weight | 299.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Coclaurine Impurity 114.
CATO supplies Coclaurine Impurity 114 (CAS 31804-74-7), a pharmacopoeial impurity reference standard (molecular formula C18H21NO3, MW 299.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H21NO3, Coclaurine Impurity 114 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 299.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Coclaurine Impurity 114 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21NO3 |
| Molecular Weight | 299.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Coclaurine Standards
- Coclaurine Impurity 6 (CAS 3472-22-8)
- Coclaurine Impurity 113 (CAS 2158198-78-6(TFA Salt))
- Coclaurine Impurity 115 (CAS CATO-C4X-275115)
- Coclaurine Impurity 15 (CAS CATO-C4X-27515)
- (+)-Coclaurine (CAS 2196-60-3)
- Coclaurine (CAS 486-39-5)
- Coclaurine Impurity 111 (CAS 2158201-34-2(TFA Salt))
- Coclaurine Impurity 112 (CAS 116331-72-7)
Recommended Standards
- Denaverine Impurity 2 (CAS 968-46-7)
- Isoprenaline Impurity 43 (CAS CATO-C4X-277543)
- Dopamine Impurity 80 (CAS CATO-C4X-190880)
- (+)-Lycopsamine Hydrochloride (CAS 480-83-1)
- Paracetamol EP Impurity M (CAS 1752-24-5)
- Venetoclax Impurity 32 (CAS CATO-C4X-249532)
- Meclozine Dihydrochloride EP Impurity C (CAS 134-85-0)
- 7-Methoxybenzo[d]thiazol-5-amine (CAS 1807009-44-4)
- N-methyl-4-((4-(trifluoromethyl)pyrimidin-2-yl)oxy)benzenesulfonamide (CAS 1858256-57-1)
- 2-(Dipropylamino)nicotinic acid (CAS 1019346-99-6)
- 3,6-Dibromo-1,8-dichloro-9H-carbazole (CAS 64389-48-6)
- 2-Chloro-5-iodonicotinic acid (CAS 59782-86-4)
- Rel-(1R,2R)-1-methylcyclopentane-1,2-diol (CAS 20557-45-3)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com