1-(Bromomethyl)-4-chloro-2-fluoro-3-methoxybenzene CAS 1323966-35-3
| CAS No. | 1323966-35-3 |
| Molecular Formula | C8H7BrClFO |
| Molecular Weight | 253.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(Bromomethyl)-4-chloro-2-fluoro-3-methoxybenzene (C8H7BrClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(Bromomethyl)-4-chloro-2-fluoro-3-methoxybenzene (CAS 1323966-35-3) is a high-purity analytical reference standard with the molecular formula C8H7BrClFO and a molecular weight of 253.50 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(Bromomethyl)-4-chloro-2-fluoro-3-methoxybenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7BrClFO |
| Molecular Weight | 253.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl/Br-containing |
Related Bromomethyl Standards
- 1-(Bromomethyl)-4-chloro-2-fluoro-5-methoxybenzene (CAS 374780-16-2)
- 2-(Bromomethyl)-3-chloro-1-fluoro-4-methoxybenzene (CAS 886499-54-3)
- 5-(Bromomethyl)-1-chloro-3-fluoro-2-methoxybenzene (CAS 886497-36-5)
- 7-(bromomethyl)-5-chloro-2,3-dihydrobenzofuran (CAS 1566320-16-8)
- 1-(Bromomethyl)-4-cyclohexylbenzene (CAS 111818-33-8)
- [4-(bromomethyl)cyclohexyl]benzene (CAS 1521961-37-4)
- 3-[4-(Bromomethyl)phenyl]thiophene (CAS 108912-09-0)
- 2-(2-(Bromomethyl)phenyl)thiophene (CAS 791078-04-1)
Recommended Standards
- 1-Bromo-5-chloro-2-ethoxy-3-fluorobenzene (CAS 1265218-86-7)
- 4-(2-bromoethoxy)-1-chloro-2-fluorobenzene (CAS 1373822-50-4)
- 2-Chloro-4-fluoro-3-methoxybenzyl bromide (CAS 1171917-24-0)
- 1-Bromo-2-(chloromethyl)-3-fluoro-4-methoxybenzene (CAS 1516298-29-5)
- Fmoc-D-Pro-Cl (CAS 171905-37-6)
- 1-(1-(4-Bromophenyl)-1H-pyrrol-3-yl)-N-(4-fluorobenzyl)methanimine (CAS 551930-64-4)
- 6-Bromo-N-methyl-2-naphthamide (CAS 426219-35-4)
- Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine (CAS 187393-00-6)
- Benzofuran-3-thiol (CAS 90590-06-0)
- 2-(1-Methyl-1,4,5,6-tetrahydropyrimidin-2-yl)-1-phenylethanone (CAS 776999-24-7)
- 3-Amino-3-(4-fluoro-3-methylphenyl)propan-1-ol (CAS 790227-22-4)
- Etelcalcetide Impurity 43 (CAS CATO-C4X-324743)
- 4-Vinylbenzoyl chloride (CAS 1565-41-9)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com