1-(Bromomethyl)-4-chloro-2-fluoro-5-methoxybenzene CAS 374780-16-2
| CAS No. | 374780-16-2 |
| Molecular Formula | C8H7BrClFO |
| Molecular Weight | 253.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Bromomethyl)-4-chloro-2-fluoro-5-methoxybenzene.
1-(Bromomethyl)-4-chloro-2-fluoro-5-methoxybenzene (CAS 374780-16-2), molecular formula C8H7BrClFO and molecular weight 253.50 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H7BrClFO, 1-(Bromomethyl)-4-chloro-2-fluoro-5-methoxybenzene contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 253.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(Bromomethyl)-4-chloro-2-fluoro-5-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7BrClFO |
| Molecular Weight | 253.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/Br-containing |
Related Bromomethyl Standards
- 1-(Bromomethyl)-4-chloro-2-fluoro-3-methoxybenzene (CAS 1323966-35-3)
- 2-(Bromomethyl)-3-chloro-1-fluoro-4-methoxybenzene (CAS 886499-54-3)
- 5-(Bromomethyl)-1-chloro-3-fluoro-2-methoxybenzene (CAS 886497-36-5)
- 7-(bromomethyl)-5-chloro-2,3-dihydrobenzofuran (CAS 1566320-16-8)
- 1-(Bromomethyl)-4-cyclohexylbenzene (CAS 111818-33-8)
- [4-(bromomethyl)cyclohexyl]benzene (CAS 1521961-37-4)
- 3-[4-(Bromomethyl)phenyl]thiophene (CAS 108912-09-0)
- 2-(2-(Bromomethyl)phenyl)thiophene (CAS 791078-04-1)
Recommended Standards
- 1-(2-Bromoethoxy)-2-chloro-4-fluorobenzene (CAS 67160-00-3)
- 1-Bromo-2-chloro-4-ethoxy-3-fluorobenzene (CAS 909122-17-4)
- 5-Bromo-1-chloro-2-ethoxy-3-fluorobenzene (CAS 1936177-81-9)
- 1-Bromo-3-chloro-2-ethoxy-4-fluorobenzene (CAS 2179038-46-9)
- 3-(3-(Methoxymethyl)benzyl)pyrrolidine (CAS 1492362-32-9)
- 2-Chloro-N-[2-(thiophen-2-yl)ethyl]propanamide (CAS 126149-36-8)
- (2,4-Diaminopyrimidin-5-yl)boronic acid (CAS 1045861-29-7)
- 1-Methoxyphenazine (CAS 2876-17-7)
- 3-Iodo-2-methylimidazo[1,2-b]pyridazine (CAS 1936592-34-5)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
- (E)-3-Hydroxy-2-(phenylsulfonyl)-3-[3-(trifluoromethyl)anilino]-2-propenenitrile (CAS 1024871-96-2)
- 1-(2,2,3,3,3-Pentafluoropropyl)piperazine (CAS 1250411-95-0)
- 5,6-Dichloro-2-(2-chloropyridin-3-yl)-1-propyl-1H-1,3-benzodiazole (CAS 338774-34-8)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
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