N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamide CAS 132442-35-4

Purity 97%+In StockPharmaceutical Standards
CAS No.132442-35-4
Molecular FormulaC19H21FN2O
Molecular Weight312.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamide CAS 132442-35-4 chemical structure

Description

N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamide (CAS 132442-35-4) is a high-purity analytical reference standard with the molecular formula C19H21FN2O and a molecular weight of 312.38 g/mol.

The molecular framework of N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamide (C19H21FN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC19H21FN2O
Molecular Weight312.38 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1994
Halogen ContentF-containing
Nitrogen Atoms2

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