Hydrocortisone impurity 42 CAS CATO-C4X-140142
| CAS No. | CATO-C4X-140142 |
| Molecular Formula | C46H62O12 |
| Molecular Weight | 806.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Hydrocortisone impurity 42 (CAS CATO-C4X-140142, C46H62O12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Hydrocortisone impurity 42 (C46H62O12) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Hydrocortisone impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C46H62O12 |
| Molecular Weight | 806.98 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Hydrocortisone Standards
- Hydrocortisone Impurity 44 (CAS 106597-71-1)
- Hydrocortisone 21 Phosphate Dimer (CAS 20513-23-9)
- Hydrocortisone EP Impurity N (CAS CATO-C4X-140114)
- Hydrocortisone Impurity 74 (CAS CATO-C4X-140174)
- Hydrocortisone Impurity 54 (CAS CATO-C4X-140154)
- Hydrocortisone Impurity 66 (CAS CATO-C4X-140166)
- Hydrocortisone Impurity 52 (CAS CATO-C4X-140152)
- Hydrocortisone 21-Octanoate (CAS 6678-14-4)
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