3-(3-Chloro-4-methylbenzenesulfonamido)thiophene-2-carboxylic acid CAS 1325304-03-7
| CAS No. | 1325304-03-7 |
| Molecular Formula | C12H10ClNO4S2 |
| Molecular Weight | 331.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(3-Chloro-4-methylbenzenesulfonamido)thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(3-Chloro-4-methylbenzenesulfonamido)thiophene-2-carboxylic acid (CAS 1325304-03-7) is a high-purity analytical reference standard with the molecular formula C12H10ClNO4S2 and a molecular weight of 331.80 g/mol.
The molecular framework of 3-(3-Chloro-4-methylbenzenesulfonamido)thiophene-2-carboxylic acid (C12H10ClNO4S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO4S2 |
| Molecular Weight | 331.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- 2-Chloro-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}acetamide (CAS 104246-27-7)
- 2-Benzyl-1-chloro-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (CAS 121105-86-0)
- 1227635-07-5 4-(2-((2-Chloro-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol ST24042817 (CAS 1227635-07-5)
- 7-Chloro-2-(3,4-dimethoxyphenyl)-6-ethyl-5-methylpyrazolo[1,5-a]pyrimidine (CAS 1464091-54-0)
- 1-(4-Chloro-6-(piperidin-1-yl)pyrimidin-2-yl)-3-phenylurea (CAS 339017-96-8)
- 2-Chloro-9-isopropyl-N-(4-methoxybenzyl)-9H-purin-6-amine (CAS 203436-13-9)
- N-(3-Chloro-4-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide (CAS 933238-18-7)
- N-(5-Chloro-2-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide (CAS 933237-92-4)
Recommended Standards
- 3-(N-Methyl4-chlorobenzenesulfonamido)thiophene-2-carboxylic acid (CAS 1638612-62-0)
- 2-{4-[(3-chlorophenyl)methyl]piperazin-1-yl}pyridine-3-carboxylic acid (CAS 1053960-15-8)
- (2-Chloropyridin-3-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone (CAS 260442-79-3)
- (E)-1-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-3-(1,3,3-trimethylindolin-2-ylidene)propan-2-one (CAS 885461-53-0)
- Tris(tri-p-tolylphosphine)platinum (CAS 33937-28-9)
- N,N,3-Trimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1253926-81-6)
- (S)-2-amino-N-(4-nitrobenzyl)propanamide (CAS 136774-66-8)
- 4-Isopropyl-4-methyloxazolidine-2,5-dione (CAS 138142-01-5)
- Pcb No. 131 (CAS 61798-70-7)
- 4-Ethoxybenzenesulfonyl Chloride (CAS 1132-17-8)
- 1-Benzyl-3-(5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one (CAS 242472-24-8)
- 5-Bromo-6-chloropyridine-2,3-diamine (CAS 1195519-49-3)
- (2E)-1,1,1,2,3,4,4,4-Octafluoro-2-butene (CAS 1516-64-9)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com