(E)-1-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-3-(1,3,3-trimethylindolin-2-ylidene)propan-2-one CAS 885461-53-0
| CAS No. | 885461-53-0 |
| Molecular Formula | C17H18ClN3O2 |
| Molecular Weight | 331.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies (E)-1-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-3-(1,3,3-trimethylindolin-2-ylidene)propan-2-one (CAS 885461-53-0), a certified reference material (molecular formula C17H18ClN3O2, MW 331.80 g/mol) for analytical method development and quality control.
The molecular framework of (E)-1-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-3-(1,3,3-trimethylindolin-2-ylidene)propan-2-one (C17H18ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (E)-1-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-3-(1,3,3-trimethylindolin-2-ylidene)propan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18ClN3O2 |
| Molecular Weight | 331.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related E Standards
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