Methyl 6,7-difluoro-4-methoxyquinoline-2-carboxylate CAS 1325307-24-1
| CAS No. | 1325307-24-1 |
| Molecular Formula | C12H9F2NO3 |
| Molecular Weight | 253.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 6,7-difluoro-4-methoxyquinoline-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 6,7-difluoro-4-methoxyquinoline-2-carboxylate (CAS 1325307-24-1), molecular formula C12H9F2NO3 and molecular weight 253.20 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 6,7-difluoro-4-methoxyquinoline-2-carboxylate (C12H9F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9F2NO3 |
| Molecular Weight | 253.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 1-Ethyl-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 101830-83-5)
- Ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 107555-38-4)
- Ethyl 6,7-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 111760-35-1)
- Ethyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 121873-01-6)
- 3,4-Difluoro-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)benzamide (CAS 1234981-40-8)
- 1-Ethyl-5,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1267361-62-5)
- 2-((5,8-Difluoro-2-methylquinolin-4-yl)oxy)acetic acid (CAS 1315346-53-2)
- Ethyl 5,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 185011-67-0)
Recommended Standards
- Methyl 2-((5,8-difluoroquinolin-4-yl)oxy)acetate (CAS 1315374-59-4)
- Rufinamide D2 Metabolite (CAS 1346597-78-1)
- 4-Ethoxy-6,8-difluoroquinoline-2-carboxylic acid (CAS 1351843-49-6)
- 1-[(2,4-difluorophenyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351847-63-6)
- 2-Methyl-5-(2-thienylcarbonyl)-1,3-thiazole-4-carboxylic acid (CAS 941868-42-4)
- 5-(Butan-2-ylsulfanyl)-4-methyl-1,2,3-thiadiazole (CAS 338419-71-9)
- 1-Methoxy-N-(thiophen-2-ylmethyl)butan-2-amine (CAS 1339525-73-3)
- 2-Amino-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one hydrochloride (CAS 1638612-83-5)
- 2-Methyl-3-phenylbutan-2-ol (CAS 3280-08-8)
- 7-Iodo-1,2,3,4-tetrahydroisoquinoline (CAS 72299-62-8)
- 2-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-6-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 955964-67-7)
- 5-(Cyclopropylmethoxy)-2-hydroxybenzaldehyde (CAS 1243461-54-2)
- Dodecyl diphenyl phosphate (CAS 2822-77-7)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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