7-Iodo-1,2,3,4-tetrahydroisoquinoline CAS 72299-62-8
| CAS No. | 72299-62-8 |
| Molecular Formula | C9H10IN |
| Molecular Weight | 259.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 259.09 g/mol gives 7-Iodo-1,2,3,4-tetrahydroisoquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 7-Iodo-1,2,3,4-tetrahydroisoquinoline (CAS 72299-62-8), a certified reference material (molecular formula C9H10IN, MW 259.09 g/mol) for analytical method development and quality control.
The molecular framework of 7-Iodo-1,2,3,4-tetrahydroisoquinoline (C9H10IN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Iodo-1,2,3,4-tetrahydroisoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10IN |
| Molecular Weight | 259.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 8-Iodo-1,2,3,4-tetrahydroquinoline (CAS 1038731-97-3)
- 7-Iodo-2,3-dihydro-1H-inden-4-amine (CAS 1359869-36-5)
- 3-Iodo-5,6,7,8-tetrahydroquinoline (CAS 1378875-98-9)
- 4-Iodo-5-methylindoline (CAS 162100-96-1)
- 6-Iodo-5-methylindoline (CAS 162100-97-2)
- 6-Iodo-1,2,3,4-tetrahydroquinoline (CAS 193354-16-4)
- 5-Iodo-6-methylindoline (CAS 1935509-31-1)
- 6-Iodo-1,2,3,4-tetrahydroisoquinoline (CAS 72299-61-7)
Recommended Standards
- 6-Iodo-2,3-dihydro-1H-inden-5-amine (CAS 944280-06-2)
- 7-Iodo-1,2,3,4-tetrahydroquinoline (CAS 939758-77-7)
- 8-Iodo-1,2,3,4-tetrahydroisoquinoline (CAS 72299-63-9)
- 5,7-Dichloro-2-(dimethylamino)-4H-3,1-benzoxazin-4-one (CAS 477853-99-9)
- 5-Ethyl-5-methyldecane (CAS 17312-74-2)
- N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 566881-55-8)
- 2-[4-(2,4-dioxohexahydropyrimidin-1-yl)phenyl]propanal (CAS 2773324-83-5)
- Ethyl 4-cyano-3-methyl-5-(thiophene-2-carboxamido)thiophene-2-carboxylate (CAS 449177-12-2)
- Ethyl 5-bromo-7-chlorobenzofuran-2-carboxylate (CAS 1643914-32-2)
- Diethyl(methyl)(vinyl)silane (CAS 18292-29-0)
- Maackiain (CAS 19908-48-6)
- 2-Chloro-6-methylbenzo[d]thiazol-4-amine (CAS 1779820-16-4)
- Carfilzomib Impurity 38 (Mixture of Diastereomers) (CAS CATO-C4X-102238)
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