Loxoprofen Impurity 60 CAS 132560-66-8
| CAS No. | 132560-66-8 |
| Molecular Formula | C11H13ClO |
| Molecular Weight | 196.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Loxoprofen Impurity 60 is closely related to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Loxoprofen Impurity 60 (CAS 132560-66-8) is a certified pharmaceutical impurity reference standard with the molecular formula C11H13ClO and a molecular weight of 196.67 g/mol.
The molecular framework of Loxoprofen Impurity 60 (C11H13ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Loxoprofen Impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13ClO |
| Molecular Weight | 196.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
Related Loxoprofen Standards
- Loxoprofen Impurity 19 (CAS 80530-55-8)
- Loxoprofen Impurity 28 (CAS 1823911-62-1)
- Loxoprofen Impurity 58 (CAS 1551612-94-2)
- Loxoprofen Impurity 36 (CAS 639857-67-3)
- Loxoprofen Impurity 45 (CAS 99807-55-3)
- Loxoprofen Impurity 17 (CAS 69673-92-3)
- Loxoprofen Impurity 59 (CAS 132560-67-9)
- Loxoprofen Impurity 62 (CAS CATO-C4X-148862)
Recommended Standards
- 4＇-Chlorovalerophenone (CAS 25017-08-7)
- 3-Chloro-6-cyclohexylpyridazine (CAS 105538-78-1)
- 951894-81-8 2-Chloro-3-(2-Methoxy-5-methylphenyl)-1-propene MFCD07775074 (CAS 951894-81-8)
- 4-Chloro-2-(piperidin-1-yl)pyridine (CAS 1086376-30-8)
- Halobetasol Impurity 10 (CAS CATO-C4X-331410)
- Baxdrostat Impurity 34 (CAS 3024295-81-3)
- Avanafil Impurity 5 (CAS 372117-54-9)
- Tert-butyl (R)-(2-(hydroxymethyl)-3-methylbutyl)carbamate (CAS 1265896-78-3)
- 6-Fluoro-3,4-dihydroquinolin-2(1H)-one (CAS 75893-82-2)
- ethyl 5-amino-1-(2-cyanoethyl)-1H-pyrazole-4-carboxylate (CAS 1007513-67-8)
- 3-Methyl-4-(methylthio)phenol (CAS 3120-74-9)
- Tert-butyl 4-hydroxy-4-methyl-3,4-dihydropyridine-1(2H)-carboxylate (CAS 2387597-72-8)
- Methyl 1-(2-cyanopyridin-4-yl)piperidine-4-carboxylate (CAS 1283441-69-9)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com