Loxoprofen Impurity 59 CAS 132560-67-9

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.132560-67-9
Molecular FormulaC12H15ClO
Molecular Weight210.70 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Loxoprofen Impurity 59 CAS 132560-67-9 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Loxoprofen Impurity 59 (CAS 132560-67-9) is a certified pharmaceutical impurity reference standard with the molecular formula C12H15ClO and a molecular weight of 210.70 g/mol.

Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Loxoprofen Impurity 59 is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 210.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H15ClO
Molecular Weight210.70 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1994
Halogen ContentCl-containing

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