4,4-Dimethyl-2-(2,4,5-trifluoro-3-methylphenyl)-4,5-dihydrooxazole CAS 132630-83-2

Purity 97%+In StockPharmaceutical Standards
CAS No.132630-83-2
Molecular FormulaC12H12F3NO
Molecular Weight243.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,4-Dimethyl-2-(2,4,5-trifluoro-3-methylphenyl)-4,5-dihydrooxazole CAS 132630-83-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4,4-Dimethyl-2-(2,4,5-trifluoro-3-methylphenyl)-4,5-dihydrooxazole (CAS 132630-83-2) is a high-purity analytical reference standard with the molecular formula C12H12F3NO and a molecular weight of 243.22 g/mol.

The molecular framework of 4,4-Dimethyl-2-(2,4,5-trifluoro-3-methylphenyl)-4,5-dihydrooxazole (C12H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), 4,4-Dimethyl-2-(2,4,5-trifluoro-3-methylphenyl)-4,5-dihydrooxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12F3NO
Molecular Weight243.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1994
Halogen ContentF-containing
Nitrogen Atoms1

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