4-(2,5-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326809-10-2
| CAS No. | 1326809-10-2 |
| Molecular Formula | C18H22F2N2O4 |
| Molecular Weight | 368.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2,5-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid.
CATO supplies 4-(2,5-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-10-2), a certified reference material (molecular formula C18H22F2N2O4, MW 368.38 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2,5-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 368.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22F2N2O4 |
| Molecular Weight | 368.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzoyl Standards
- 4-(3,5-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326812-08-1)
- 4-(2,4-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-14-2)
- 4-(3,4-Difluorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-21-1)
- N-(5-(3,5-Difluorobenzoyl)-1H-indazol-3-yl)-2,2,2-trifluoroacetamide (CAS 1108745-14-7)
- 3-(3-(2,5-Difluorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide (CAS 858118-67-9)
- 4-(3-(2,5-Difluorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide (CAS 858118-62-4)
- 5-(2,6-Difluorobenzoyl)-7-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861206-91-9)
- 4-(3,5-Difluorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-43-8)
Recommended Standards
- (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-acetamidopropanoic acid (CAS 1313054-72-6)
- SPIRO[1,3-DIOXOLANE-2,9’-[9H]FLUORENE]-4,5-DICARBOXYLIC ACID DIETHYL ESTER (CAS 129178-60-5)
- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one (CAS 129145-53-5)
- 3-(Ethoxycarbonyl)-5-methyl-1-(4-phenoxyphenyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264044-02-1)
- (5-Methylpyrimidin-2-yl)methanamine dihydrochloride (CAS 930272-59-6)
- 4-(tert-Butyl)-2-methylpyridine (CAS 97691-20-8)
- tert-Butyl 2-(((4-methylpyrimidin-2-yl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 1261231-39-3)
- (5-(Aminomethyl)thiophen-2-yl)(thiophen-2-yl)methanone hydrobromide (CAS 1448046-01-2)
- 7,9-Bis(2,6-bis((R)-1-(3,5-dimethylphenyl)ethyl)-4-methylphenyl)-7H-acenaphtho[1,2-d]imidazol-9-ium chloride (CAS 2212005-57-5)
- Relebactam Impurity 98 (CAS 2650127-84-5)
- 4-Cyanobenzyl acetate (CAS 21388-95-4)
- (+)-proto-Quercitol (CAS 488-73-3)
- 7-(tert-Butyl)-3-(2,6-difluorophenyl)-6-((1-ethyl-1h-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 286456-46-0)
- Liraglutide (CAS 204656-20-2)
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