4-(3-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326809-11-3
| CAS No. | 1326809-11-3 |
| Molecular Formula | C18H23ClN2O4 |
| Molecular Weight | 366.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(3-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-11-3), a certified reference material (molecular formula C18H23ClN2O4, MW 366.84 g/mol) for analytical method development and quality control.
Structurally, 4-(3-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C18H23ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 366.84 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23ClN2O4 |
| Molecular Weight | 366.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzoyl Standards
- 4-(2-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-25-9)
- 4-(4-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-93-1)
- Ethyl 2-{2-[(4-chlorobenzoyl)amino]-1,3-thiazol-4-yl}-2-(methoxyimino)acetate (CAS 1024870-00-5)
- Methyl 3-[(3-chlorobenzoyl)amino]-3-(1-naphthyl)propanoate (CAS 439108-87-9)
- 16-(4-Chlorobenzoyl)-11,15-dioxa-16-azatetracyclo[8.7.0.0^{2,7}.0^{13,17}]heptadeca-1(10),2(7),3,5,8-pentaene (CAS 477853-75-1)
- (E)-2-(2-Chlorobenzoyl)-3-[4-fluoro-3-(trifluoromethyl)anilino]-2-propenenitrile (CAS 1025596-46-6)
- N'-(3-chlorobenzoyl)naphtho[2,1-b]furan-2-carbohydrazide (CAS 478259-75-5)
- 5-(4-Chlorobenzoyl)-N2-(4-chlorophenyl)-1,3-thiazole-2,4-diamine (CAS 107401-72-9)
Recommended Standards
- Dehydro Indapamide-d3 (CAS 1185057-48-0)
- 1-(4-((3'-Chloro-6-methoxy-[1,1'-biphenyl]-3-yl)methyl)phenyl)urea (CAS 1155877-97-6)
- 2-(4-Benzylpiperazin-1-yl)-3-chloronaphthalene-1,4-dione (CAS 104309-93-5)
- 2-Chloro-4-[4-(1-naphthyl)phenyl]quinazoline (CAS 1373265-62-3)
- (3R)-3-chloropyrrolidin-2-one (CAS 307316-12-7)
- tert-Butyl N-(3-fluoropiperidin-4-yl)carbamate (CAS 1228631-81-9)
- (3,6-Dichloropyridin-2-yl)methanol (CAS 58804-10-7)
- N-(4-methoxybenzyl)-2-(2-phenylacetyl)benzamide (CAS 329929-12-6)
- 5-Methoxy-2-(4-(methylsulfonyl)piperazine-1-carbonyl)-4H-pyran-4-one (CAS 1040661-96-8)
- b-Methyl-a,a-diphenyl-4-morpholinebutanenitrile (CAS 1704-70-7)
- 4-((5,6-Dimethyl-1H-benzo[d]imidazol-1-yl)sulfonyl)benzenesulfonamide (CAS 606131-22-0)
- 5-Chloro-3-methyleneisoindolin-1-one (CAS 1239331-77-1)
- 1-Benzyl-N,3,3-trimethylpiperidin-4-amine (CAS 473838-38-9)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
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