4-[3,5-Bis(trifluoromethyl)benzoyl]-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid CAS 1326810-27-8
| CAS No. | 1326810-27-8 |
| Molecular Formula | C22H25F6NO4 |
| Molecular Weight | 481.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 481.43 g/mol gives 4-[3,5-Bis(trifluoromethyl)benzoyl]-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-[3,5-Bis(trifluoromethyl)benzoyl]-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-27-8), molecular formula C22H25F6NO4 and molecular weight 481.43 g/mol, is a CATO reference standard with documented purity and traceability.
4-[3,5-Bis(trifluoromethyl)benzoyl]-8-tert-Butyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (C22H25F6NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25F6NO4 |
| Molecular Weight | 481.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
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Recommended Standards
- PG-01037, >98% (HPLC) (CAS 790658-27-4)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phosphonomethyl)phenyl)propanoic acid (CAS 229180-65-8)
- N-(2,4-dichlorophenyl)-2-((2-((4-methylphenyl)sulfonamido)phenyl)thio)acetamide (CAS 477869-04-8)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(phosphonomethyl)phenyl)propanoic acid (CAS 229180-64-7)
- 4-[6-(4-Trifluoromethylphenyl)-pyridin-3-yl]-pyrimidin-2-ylamine (CAS 1360951-54-7)
- 3-Bromo-4-isopropoxybenzoic Acid (CAS 213598-20-0)
- Benzene-1,2,4,5-tetrayltetrakis(methylene)tetrabutyltetrakis(carbonotrithioate) (CAS 1313038-04-8)
- 5-Amino-1-(2-hydroxyethyl)pyrazole-4-carboxylic Acid (CAS 58046-50-7)
- 5-Fluoro-2-phenyl-pyrimidin-4-ol (CAS 143328-90-9)
- 4-(Prop-1-en-2-yl)-2,3-dihydro-1H-inden-1-one (CAS 1380389-85-4)
- Ethyl 2-(2-(2-aminothiazol-4-yl)phenoxy)acetate (CAS 1082129-47-2)
- 2-(1-Benzyl-3-piperidinyl)acetic acid (CAS 64995-90-0)
- 90996-04-6 17-(4-Decylphenoxy)-3,6,9,12,15-pentaoxaheptadecan-1-ol DTXSID90756882 (CAS 90996-04-6)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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