4-(2,4-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326814-99-6
| CAS No. | 1326814-99-6 |
| Molecular Formula | C17H20Cl2N2O4 |
| Molecular Weight | 387.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2,4-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid.
4-(2,4-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326814-99-6) is a high-purity analytical reference standard with the molecular formula C17H20Cl2N2O4 and a molecular weight of 387.26 g/mol.
The molecular framework of 4-(2,4-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C17H20Cl2N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2,4-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20Cl2N2O4 |
| Molecular Weight | 387.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorobenzoyl Standards
- 4-(3,5-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326814-28-1)
- 4-(3,4-Dichlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326815-15-9)
- 4-(2,4-Dichlorobenzoyl)-N-phenethyl-1H-pyrrole-2-carboxamide (CAS 439109-69-0)
- N-((3,4-Dichlorobenzoyl)oxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88758-06-9)
- 8-(2,4-Dichlorobenzoyl)-3-propyl-1,3,8-triazaspiro[4.5]decane-2,4-dione (CAS 1021210-54-7)
- 4-(2,3-Dichlorobenzoyl)-N-(4-fluorobenzyl)-1H-pyrrole-2-carboxamide (CAS 477870-42-1)
- (2Z)-3-[4-(2,4-Dichlorobenzoyl)-1-methyl-1H-pyrrol-2-yl]-2-(pyridin-2-yl)prop-2-enenitrile (CAS 246022-15-1)
- N-(2,4-Dichlorobenzoyl)-N-(4-isopropyl-3-methylphenyl)thiourea (CAS 866151-66-8)
Recommended Standards
- Macitentan Impurity 4 (CAS 2365406-85-3)
- 2,2'-((2,6-Dichloro-8-(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-4-yl)azanediyl)diethanol (CAS 1449029-15-5)
- 4-(4-Bromophenyl)-2-[4-(3-fluoropropoxy)phenyl]pyrimidine (CAS 477856-56-7)
- 2-Chloro-3-(4-(3-chlorophenyl)piperazin-1-yl)naphthalene-1,4-dione (CAS 179121-03-0)
- (2-Chloroquinolin-7-yl)methanol (CAS 1823116-42-2)
- 6-Methyl-1,8-naphthyridine-2,5(1H,8H)-dione (CAS 57773-16-7)
- 3,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS 35480-55-8)
- 2-(3-Amino-5-chloro-4-hydroxybenzyl)isoindoline-1,3-dione (CAS 696650-05-2)
- 6-(Trifluoromethyl)-1H-indazol-5-amine (CAS 1000373-75-0)
- 2-(4-(Methylsulfonyl)piperazin-1-yl)ethan-1-ol (CAS 72388-13-7)
- 2-((5-Methyl-1H-benzo[d]imidazol-2-yl)thio)-N-(4-methylbenzyl)acetamide (CAS 852413-77-5)
- 1-((1H-pyrazol-1-yl)methyl)-1H-pyrazol-3-amine (CAS 1006472-78-1)
- 2-(Dimethylamino)-2-(1-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1218240-85-7)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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