6,7-Difluoro-1-(4-methylbenzyl)-3-(m-tolylsulfonyl)quinolin-4(1H)-one CAS 1326863-21-1
| CAS No. | 1326863-21-1 |
| Molecular Formula | C24H19F2NO3S |
| Molecular Weight | 439.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6,7-Difluoro-1-(4-methylbenzyl)-3-(m-tolylsulfonyl)quinolin-4(1H)-one.
CATO supplies 6,7-Difluoro-1-(4-methylbenzyl)-3-(m-tolylsulfonyl)quinolin-4(1H)-one (CAS 1326863-21-1), a certified reference material (molecular formula C24H19F2NO3S, MW 439.47 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 6,7-Difluoro-1-(4-methylbenzyl)-3-(m-tolylsulfonyl)quinolin-4(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 439.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H19F2NO3S |
| Molecular Weight | 439.47 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- 6,7-Difluoro-1-(3-methylbenzyl)-3-(m-tolylsulfonyl)quinolin-4(1H)-one (CAS 1326823-02-2)
- 2,6-Difluoro-N-((3-(naphthalen-2-yl)-1-phenyl-1H-pyrazol-4-yl)methyl)benzamide (CAS 956781-80-9)
- N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide (CAS 918505-61-0)
- Methyl 2-(4-(5,5-difluoro-7-(thiophen-2-yl)-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)phenoxy)acetate (CAS 150152-63-9)
- 2,3-Difluoro-4''-Heptyl-4-Pentyl-1,1':4',1''-Terphenyl (CAS 121218-85-7)
- 2,3-Difluoro-4-Heptyl-4''-Pentyl-1,1':4',1''-Terphenyl (CAS 121218-90-4)
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Recommended Standards
- 1-Benzyl-3-((3,4-dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1326942-25-9)
- Fmoc-D-Cit(Ac)-OH (CAS CATO-CPTD788603)
- (3S,4S)-3,4-Bis(diphenylphosphino)pyrrolidine (CAS 145693-67-0)
- Alogliptin Impurity 91 (CAS CATO-C4X-109991)
- N-(5-(4-Aminophenoxy)pentyl)-4-hydroxybenzamide (CAS 108367-29-9)
- 3-{[(tert-butoxy)carbonyl](ethyl)amino}butanoic acid (CAS 1343386-72-0)
- Ethyl 1-phenyl-1h,4h,5h,6h-cyclopenta[c]pyrazole-3-carboxylate (CAS 97377-96-3)
- ethyl 2-cyano-2-ethyl-3-methylpentanoate (CAS 71172-92-4)
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