N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide CAS 918505-61-0
| CAS No. | 918505-61-0 |
| Molecular Formula | C22H18F2N4O2S |
| Molecular Weight | 440.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide (CAS 918505-61-0), molecular formula C22H18F2N4O2S and molecular weight 440.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide (C22H18F2N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H18F2N4O2S |
| Molecular Weight | 440.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Methyl 5-(3,4-dimethoxyphenyl)-2-(furan-2-ylmethylene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 331454-82-1)
- Vortioxetine Impurity 53 (CAS CATO-C4X-105653)
- 5-(4-Hydroxy-3-methoxybenzylidene)-2-(4-(4-nitrophenyl)piperazin-1-yl)thiazol-4(5H)-one (CAS 844447-18-3)
- Tazobactam Impurity 24 (CAS 89051-49-0)
- (1S,2S,4S,5R)-1-(Anthracen-9-ylmethyl)-2-((R)-(benzyloxy)(quinolin-4-yl)methyl)-5-ethylquinuclidin-1-ium bromide (CAS 229482-68-2)
- Lithium 2-chloro-3,6-difluorobenzenesulfinate (CAS 1233505-63-9)
- 3-(6-BROMOPYRIDIN-3-YL)PROPANOIC ACID (CAS 1036227-86-7)
- Methyl 1-((4-methyl-1H-pyrazol-1-yl)methyl)-4-nitro-1H-pyrazole-3-carboxylate (CAS 1260379-30-3)
- (2-methyl-2-phenylpropyl)(propyl)amine hydrochloride (CAS 1354951-15-7)
- N-Isopropyl-N-(pyrrolidin-3-ylmethyl)acetamide (CAS 1353971-97-7)
- (E)-5-Octadecene (CAS 7206-21-5)
- Karenitecin (Cositecan) (CAS 203923-89-1)
- 3,4-Difluorophenylhydrazine Hydrochloride (CAS 875664-54-3)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
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