2-Amino-4-chloro-N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]benzamide D3 CAS 1330169-87-3
| CAS No. | 1330169-87-3 |
| Molecular Formula | - |
| Molecular Weight | 424.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Amino-4-chloro-N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]benzamide D3 (C19H15D3ClF2N5O2) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-Amino-4-chloro-N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]benzamide D3 (CAS 1330169-87-3), a certified reference material (molecular formula C19H15D3ClF2N5O2, MW 424.85 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-4-chloro-N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]benzamide D3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15D3ClF2N5O2 |
| Molecular Weight | 424.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
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Recommended Standards
- Tivozanib Impurity 19 (CAS CATO-C4X-340019)
- Ethyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-phenylbenzofuran-3-carboxylate (CAS 307552-05-2)
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- N-{[(1Z)-[(benzenesulfonyl)imino](methylsulfanyl)methyl]amino}-3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS 338407-81-1)
- 5-Bromo-1-(cyclopropylmethyl)-1,2-dihydropyridin-2-one (CAS 1114573-41-9)
- (3-Methyl-1-(pyridin-3-yl)-1H-pyrazol-4-yl)boronic acid (CAS 1394837-47-8)
- (11aR)-N,N-Dicyclohexyl-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine (CAS 500997-68-2)
- 5-((Dimethylamino)methyl)furan-2-carboxylic acid hydrochloride (CAS 1185300-64-4)
- 9-(Cyclopropylmethyl)-3-phenyl-9-azabicyclo[3.3.1]nonan-3-ol (CAS 1211403-26-7)
- 1-(6-Chlorobenzo[d]thiazol-2-yl)azetidine-3-carboxylic acid (CAS 1283107-95-8)
- 1-(Diphenylmethylene)-2-(triphenylphosphoranylidene)hydrazine (CAS 1109-01-9)
- 1-(2-Chlorophenyl)-2-(cyclopentylsulfanyl)ethan-1-one (CAS 726149-06-0)
- 1H-Benzimidazolium, 5,6-dichloro-1-ethyl-2-methyl-3-(4-sulfobutyl)-, inner salt (CAS 32634-37-0)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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