Ethyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-phenylbenzofuran-3-carboxylate CAS 307552-05-2
| CAS No. | 307552-05-2 |
| Molecular Formula | C24H18ClFO4 |
| Molecular Weight | 424.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-phenylbenzofuran-3-carboxylate.
Ethyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-phenylbenzofuran-3-carboxylate (CAS 307552-05-2), molecular formula C24H18ClFO4 and molecular weight 424.85 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-phenylbenzofuran-3-carboxylate (C24H18ClFO4) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-phenylbenzofuran-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18ClFO4 |
| Molecular Weight | 424.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
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Recommended Standards
- 2-Amino-4-chloro-N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]benzamide D3 (CAS 1330169-87-3)
- N-{[(1Z)-[(benzenesulfonyl)imino](methylsulfanyl)methyl]amino}-3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS 338407-81-1)
- Tivozanib Impurity 19 (CAS CATO-C4X-340019)
- 4-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrobenzoyl}morpholine (CAS 339276-57-2)
- Ethyl 3-oxo-3-(thiazol-2-ylamino)propanoate (CAS 58199-16-9)
- (S)-5-Benzyl-2-(4-(tert-butyl)phenyl)-6,8-dihydro-5H-[1,2,4]triazolo[3,4-c][1,4]oxazin-2-ium tetrafluoroborate (CAS 2650518-25-3)
- 2-Chloro-3,5-difluorobenzophenone (CAS 746651-97-8)
- Ethyl 2-(2-amino-1H-imidazol-1-yl)acetate (CAS 110295-88-0)
- Cyclopentyl(1H-indol-3-yl)methanone (CAS 117954-38-8)
- 2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)-1-(azepan-1-yl)ethan-1-one (CAS 848904-31-4)
- 3,5-Dichloro-4-iodopyridine (CAS 343781-41-9)
- 2-Hexadecyl-Cctadecanoic Acid (CAS 89547-15-9)
- 8-Fluorospiro[chromane-2,4'-piperidine] hydrochloride (CAS 1469468-21-0)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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