Methyl 2-(6-Nitro-3-indolyl)-2-oxoacetate CAS 133053-91-5
| CAS No. | 133053-91-5 |
| Molecular Formula | C11H8N2O5 |
| Molecular Weight | 248.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-(6-Nitro-3-indolyl)-2-oxoacetate (CAS 133053-91-5) is a high-purity analytical reference standard with the molecular formula C11H8N2O5 and a molecular weight of 248.19 g/mol.
Methyl 2-(6-Nitro-3-indolyl)-2-oxoacetate (C11H8N2O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8N2O5 |
| Molecular Weight | 248.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 3-Nitro-1-[(4-nitrophenyl)methyl]-1h-pyrazole (CAS 1006499-87-1)
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- 4-Nitro-1-[(3-nitrophenyl)methyl]-1h-pyrazole (CAS 1240569-46-3)
- Methyl 6-nitro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 16133-46-3)
- Methyl 2-(5-Nitro-3-indolyl)-2-oxoacetate (CAS 163160-57-4)
- Methyl 3-nitro-4-(1H-1,2,4-triazol-1-yl)-benzenecarboxylate (CAS 167626-49-5)
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Recommended Standards
- 5-(1,3-Dioxaindan-5-yloxy)furan-2-carboxylic acid (CAS 1263212-96-9)
- Methyl 4-hydroxy-6-nitroquinoline-2-carboxylate (CAS 1373835-07-4)
- 4-Methyl-2-(4-nitrophenyl)oxazole-5-carboxylic acid (CAS 1243440-61-0)
- Methyl 5-(2-Nitrophenyl)isoxazole-3-carboxylate (CAS 1375064-51-9)
- 8-Benzyl-3-oxa-8-azabicyclo[3.2.1]octane (CAS 1187087-20-2)
- 4-Chloro-6-methoxycinnoline-3-carbonitrile (CAS 1239784-36-1)
- Ethyl 2-{4-bromo-2-methoxy-6-[(1Z)-(phenylimino)methyl]phenoxy}acetate (CAS 338750-63-3)
- 1-(2,2-Difluoroethyl)piperidin-3-one (CAS 150-85-7)
- 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole (CAS 59646-16-1)
- 4-(Allylamino)-4-oxobutanoic acid (CAS 16606-43-2)
- 2-(5-Amino-3-ethyl-4-(methylsulfonyl)-1H-pyrazol-1-yl)ethanol (CAS 1708436-67-2)
- 4-Bromo-3-(hydroxymethyl)biphenyl (CAS 22156-72-5)
- 5-benzyl-2-chloropyrimidine (CAS 859209-15-7)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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